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Highly Efficient Genome Modification of Cultured Primordial Germ Cells with Lentiviral Vectors to Generate Transgenic Songbirds

The ability to genetically manipulate organisms has led to significant insights into functional genomics in many species. In birds, manipulation of the genome is hindered by the inaccessibility of the one-cell embryo. During embryonic development, avian primordial germ cells (PGCs) migrate through t...

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Detalles Bibliográficos
Autores principales:	Gessara, Ivana, Dittrich, Falk, Hertel, Moritz, Hildebrand, Staffan, Pfeifer, Alexander, Frankl-Vilches, Carolina, McGrew, Mike, Gahr, Manfred
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072032/ https://www.ncbi.nlm.nih.gov/pubmed/33740464 http://dx.doi.org/10.1016/j.stemcr.2021.02.015

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