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Comparative Analysis of Patient-Matched PDOs Revealed a Reduction in OLFM4-Associated Clusters in Metastatic Lesions in Colorectal Cancer

Metastasis is the major cause of cancer-related death, but whether metastatic lesions exhibit the same cellular composition as primary tumors has yet to be elucidated. To investigate the cellular heterogeneity of metastatic colorectal cancer (CRC), we established 72 patient-derived organoids (PDOs)...

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Detalles Bibliográficos
Autores principales:	Okamoto, Takuya, duVerle, David, Yaginuma, Katsuyuki, Natsume, Yasuko, Yamanaka, Hitomi, Kusama, Daisuke, Fukuda, Mayuko, Yamamoto, Mayuko, Perraudeau, Fanny, Srivastava, Upasna, Kashima, Yukie, Suzuki, Ayako, Kuze, Yuuta, Takahashi, Yu, Ueno, Masashi, Sakai, Yoshiharu, Noda, Tetsuo, Tsuda, Koji, Suzuki, Yutaka, Nagayama, Satoshi, Yao, Ryoji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Resource
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072036/ https://www.ncbi.nlm.nih.gov/pubmed/33711267 http://dx.doi.org/10.1016/j.stemcr.2021.02.012

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