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Reconciling Flux Experiments for Quantitative Modeling of Normal and Malignant Hematopoietic Stem/Progenitor Dynamics
Hematopoiesis serves as a paradigm for how homeostasis is maintained within hierarchically organized cell populations. However, important questions remain as to the contribution of hematopoietic stem cells (HSCs) toward maintaining steady state hematopoiesis. A number of in vivo lineage labeling and...
Autores principales: | Takahashi, Munetomo, Barile, Melania, Chapple, Richard H., Tseng, Yu-jung, Nakada, Daisuke, Busch, Katrin, Fanti, Ann-Kathrin, Säwén, Petter, Bryder, David, Höfer, Thomas, Göttgens, Berthold |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072066/ https://www.ncbi.nlm.nih.gov/pubmed/33770496 http://dx.doi.org/10.1016/j.stemcr.2021.02.020 |
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