Cargando…
A complex of distal appendage–associated kinases linked to human disease regulates ciliary trafficking and stability
Cilia biogenesis is a complex, multistep process involving the coordination of multiple cellular trafficking pathways. Despite the importance of ciliogenesis in mediating the cellular response to cues from the microenvironment, we have only a limited understanding of the regulation of cilium assembl...
Autores principales: | Loukil, Abdelhalim, Barrington, Chloe, Goetz, Sarah C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072220/ https://www.ncbi.nlm.nih.gov/pubmed/33846249 http://dx.doi.org/10.1073/pnas.2018740118 |
Ejemplares similares
-
The Meckel syndrome- associated protein MKS1 functionally interacts with components of the BBSome and IFT complexes to mediate ciliary trafficking and hedgehog signaling
por: Goetz, Sarah C., et al.
Publicado: (2017) -
Multiple ciliary localization signals control INPP5E ciliary targeting
por: Cilleros-Rodriguez, Dario, et al.
Publicado: (2022) -
Myristoylated Neuronal Calcium Sensor-1 captures the ciliary vesicle at distal appendages
por: Kanie, Tomoharu, et al.
Publicado: (2023) -
GJA1 depletion causes ciliary defects by affecting Rab11 trafficking to the ciliary base
por: Jang, Dong Gil, et al.
Publicado: (2022) -
Sphingosine kinases regulate ER contacts with late endocytic organelles and cholesterol trafficking
por: Palladino, Elisa N. D., et al.
Publicado: (2022)