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GTSE1 promotes SNAIL1 degradation by facilitating its nuclear export in hepatocellular carcin oma cells

Snail family transcriptional repressor 1 (SNAIL1) is a master inducer of the epithelial-to-mesenchymal transition (EMT) process, contributing to tumor metastasis and recurrence. Our previous study reported that G(2) and S phase-expressed-1 (GTSE1) served a role in regulating SNAIL1 expression in hep...

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Detalles Bibliográficos
Autores principales: Li, Shan-Shan, Chen, Dong-Mei, Chen, Lu-Biao, Wei, Huan, Wang, Jia-Liang, Xiao, Jian, Huang, Yue-Hua, Lian, Yi-Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072310/
https://www.ncbi.nlm.nih.gov/pubmed/33880590
http://dx.doi.org/10.3892/mmr.2021.12093