Cargando…
Impaired TRPV4-eNOS signaling in trabecular meshwork elevates intraocular pressure in glaucoma
Primary Open Angle Glaucoma (POAG) is the most common form of glaucoma that leads to irreversible vision loss. Dysfunction of trabecular meshwork (TM) tissue, a major regulator of aqueous humor (AH) outflow resistance, is associated with intraocular pressure (IOP) elevation in POAG. However, the und...
Autores principales: | Patel, Pinkal D., Chen, Yen-Lin, Kasetti, Ramesh B., Maddineni, Prabhavathi, Mayhew, William, Millar, J. Cameron, Ellis, Dorette Z., Sonkusare, Swapnil K., Zode, Gulab S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072326/ https://www.ncbi.nlm.nih.gov/pubmed/33853948 http://dx.doi.org/10.1073/pnas.2022461118 |
Ejemplares similares
-
Ex-vivo cultured human corneoscleral segment model to study the effects of glaucoma factors on trabecular meshwork
por: Kasetti, Ramesh B., et al.
Publicado: (2020) -
Correction: Ex-vivo cultured human corneoscleral segment model to study the effects of glaucoma factors on trabecular meshwork
por: Kasetti, Ramesh B., et al.
Publicado: (2020) -
Increased synthesis and deposition of extracellular matrix proteins leads to endoplasmic reticulum stress in the trabecular meshwork
por: Kasetti, Ramesh B., et al.
Publicado: (2017) -
CNS axonal degeneration and transport deficits at the optic nerve head precede structural and functional loss of retinal ganglion cells in a mouse model of glaucoma
por: Maddineni, Prabhavathi, et al.
Publicado: (2020) -
Expression of Mutant Myocilin Induces Abnormal Intracellular Accumulation of Selected Extracellular Matrix Proteins in the Trabecular Meshwork
por: Kasetti, Ramesh B., et al.
Publicado: (2016)