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Impaired TRPV4-eNOS signaling in trabecular meshwork elevates intraocular pressure in glaucoma

Primary Open Angle Glaucoma (POAG) is the most common form of glaucoma that leads to irreversible vision loss. Dysfunction of trabecular meshwork (TM) tissue, a major regulator of aqueous humor (AH) outflow resistance, is associated with intraocular pressure (IOP) elevation in POAG. However, the und...

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Detalles Bibliográficos
Autores principales: Patel, Pinkal D., Chen, Yen-Lin, Kasetti, Ramesh B., Maddineni, Prabhavathi, Mayhew, William, Millar, J. Cameron, Ellis, Dorette Z., Sonkusare, Swapnil K., Zode, Gulab S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072326/
https://www.ncbi.nlm.nih.gov/pubmed/33853948
http://dx.doi.org/10.1073/pnas.2022461118

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