Regulation of longevity by depolarization-induced activation of PLC-β–IP(3)R signaling in neurons

Mitochondrial ATP production is a well-known regulator of neuronal excitability. The reciprocal influence of plasma-membrane potential on ATP production, however, remains poorly understood. Here, we describe a mechanism by which depolarized neurons elevate the somatic ATP/ADP ratio in Drosophila glu...

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Detalles Bibliográficos
Autores principales: Wong, Ching-On, Karagas, Nicholas E., Jung, Jewon, Wang, Qiaochu, Rousseau, Morgan A., Chao, Yufang, Insolera, Ryan, Soppina, Pushpanjali, Collins, Catherine A., Zhou, Yong, Hancock, John F., Zhu, Michael X., Venkatachalam, Kartik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072327/
https://www.ncbi.nlm.nih.gov/pubmed/33859040
http://dx.doi.org/10.1073/pnas.2004253118

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