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The impact of identity by descent on fitness and disease in dogs

Domestic dogs have experienced population bottlenecks, recent inbreeding, and strong artificial selection. These processes have simplified the genetic architecture of complex traits, allowed deleterious variation to persist, and increased both identity-by-descent (IBD) segments and runs of homozygos...

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Detalles Bibliográficos
Autores principales: Mooney, Jazlyn A., Yohannes, Abigail, Lohmueller, Kirk E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072400/
https://www.ncbi.nlm.nih.gov/pubmed/33853941
http://dx.doi.org/10.1073/pnas.2019116118