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Pharmacokinetic and Pharmacodynamic Considerations in Relation to Calcineurin Usage in Elderly Kidney Transplant Recipients

This review summarizes how possible age-related changes in tacrolimus and cyclosporine pharmacokinetics and pharmacodynamics may influence drug dosing and monitoring in the elderly, and highlights how micro-sampling may be useful in this cohort in the future. Advancing biological age leads to physio...

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Detalles Bibliográficos
Autores principales:	Cossart, Amelia R., Isbel, Nicole M., Scuderi, Carla, Campbell, Scott B., Staatz, Christine E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072471/ https://www.ncbi.nlm.nih.gov/pubmed/33912051 http://dx.doi.org/10.3389/fphar.2021.635165

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