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Adjunctive S100A8/A9 Immunomodulation Hinders Ciprofloxacin Resistance in Pseudomonas aeruginosa in a Murine Biofilm Wound Model
OBJECTIVE: Pseudomonas aeruginosa is known to contribute to the pathogenesis of chronic wounds by biofilm-establishment with increased tolerance to host response and antibiotics. The neutrophil-factor S100A8/A9 has a promising adjuvant effect when combined with ciprofloxacin, measured by quantitativ...
Autores principales: | Laulund, Anne S., Schwartz, Franziska, Trøstrup, Hannah, Thomsen, Kim, Christophersen, Lars, Calum, Henrik, Ciofu, Oana, Høiby, Niels, Moser, Claus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072475/ https://www.ncbi.nlm.nih.gov/pubmed/33912476 http://dx.doi.org/10.3389/fcimb.2021.652012 |
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