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Identification of Two Novel Peptides That Inhibit α-Synuclein Toxicity and Aggregation
Aggregation of α-synuclein (αSyn) into proteinaceous deposits is a pathological hallmark of a range of neurodegenerative diseases including Parkinson’s disease (PD). Numerous lines of evidence indicate that the accumulation of toxic oligomeric and prefibrillar αSyn species may underpin the cellular...
Autores principales: | Popova, Blagovesta, Wang, Dan, Rajavel, Abirami, Dhamotharan, Karthikeyan, Lázaro, Diana F., Gerke, Jennifer, Uhrig, Joachim F., Hoppert, Michael, Outeiro, Tiago F., Braus, Gerhard H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072481/ https://www.ncbi.nlm.nih.gov/pubmed/33912013 http://dx.doi.org/10.3389/fnmol.2021.659926 |
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