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Synthesis and Antiproliferative Activity of Triazoles Based on 2-Azabicycloalkanes
A library of 21 novel chiral 1,2,3-triazole-based 2-azabicycloalkane conjugates was designed and synthesized using the copper(I)-catalyzed click reaction. The obtained hybrids were assessed for their antiproliferative potency against three selected human cancer cell lines: Hs294T (melanoma), MIA PaC...
Autores principales: | Steppeler, Franz, Kłopotowska, Dagmara, Wietrzyk, Joanna, Wojaczyńska, Elżbieta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072719/ https://www.ncbi.nlm.nih.gov/pubmed/33919613 http://dx.doi.org/10.3390/ma14082039 |
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