Cargando…

In Vitro Activity of a Novel Siderophore-Cephalosporin LCB10-0200 (GT-1), and LCB10-0200/Avibactam, against Carbapenem-Resistant Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii, and Pseudomonas aeruginosa Strains at a Tertiary Hospital in Korea

The siderophore–antibiotic conjugate LCB10-0200 (a.k.a. GT-1) has been developed to combat multidrug-resistant Gram-negative bacteria. In this study, the in vitro activity of LCB10-0200 and LCB10-0200/avibactam (AVI) has been investigated against carbapenem-resistant Escherichia coli, Klebsiella pne...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nguyen, Le Phuong, Park, Chul Soon, Pinto, Naina Adren, Lee, Hyunsook, Seo, Hyun Soo, Vu, Thao Nguyen, Mai, Hung, Pham, An H. T., Jang, Eris, Cho, Young Lag, Goglin, Karrie, Nguyen, Kevin, White, Richard, D’Souza, Roshan, Fouts, Derrick E., Yong, Dongeun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072773/ https://www.ncbi.nlm.nih.gov/pubmed/33923801 http://dx.doi.org/10.3390/ph14040370

Ejemplares similares

Antibacterial Activity of LCB10-0200 against Klebsiella pneumoniae
por: Oh, Sang-Hun, et al.
Publicado: (2021)

In Vitro Activity of a Novel Siderophore-Cephalosporin, GT-1 and Serine-Type β-Lactamase Inhibitor, GT-055, against Escherichia coli, Klebsiella pneumoniae and Acinetobacter spp. Panel Strains
por: Nguyen, Le Phuong, et al.
Publicado: (2020)

In Vivo Activity of LCB 01-0699, a Prodrug of LCB 01-0648, against Staphylococcus aureus
por: Oh, Sang-Hun, et al.
Publicado: (2017)

In Vitro Activities of LCB 01-0648, a Novel Oxazolidinone, against Gram-Positive Bacteria
por: Oh, Sang-Hun, et al.
Publicado: (2017)

EHMTI-0200. Aerobic exercise training at the ventilatory threshold prevents migraine and improves mood
por: Oliveira, AB, et al.
Publicado: (2014)

Effect of food on the pharmacokinetic characteristics of a single oral dose of LCB01-0371, a novel oxazolidinone antibiotic
por: Sunwoo, Jung, et al.
Publicado: (2018)

Early Bactericidal Activity of Delpazolid (LCB01-0371) in Patients with Pulmonary Tuberculosis
por: Kim, Ju Sang, et al.
Publicado: (2022)

Predominance of clathrin light chain LCb correlates with the presence of a regulated secretory pathway
Publicado: (1990)

Higher order mode (HOM) induced longitudinal coupled bunch (LCB) instabilities at the SRS
por: McIntosh, P A, et al.
Publicado: (1996)

Resistome Profiles, Plasmid Typing, and Whole-Genome Phylogenetic Tree Analyses of Bla(NDM-9) and Mcr-1 Co-Harboring Escherichia coli ST617 from a Patient without a History of Farm Exposure in Korea
por: Nguyen, Le Phuong, et al.
Publicado: (2019)

Molecular Characterization of Rice OsLCB2a1 Gene and Functional Analysis of its Role in Insect Resistance
por: Begum, Mahfuj A., et al.
Publicado: (2016)

Role of AmpG in the resistance to β-lactam agents, including cephalosporins and carbapenems: candidate for a novel antimicrobial target
por: D’Souza, Roshan, et al.
Publicado: (2021)

Infusion peridurial de fentanil y ropivacaina al 0.200%, 0.160% para analgesia post operatoria en cirugia oncologica
por: Martinez Zayas, Ruhama Eva
Publicado: (2016)

Randomised clinical trial: a leucine‐metformin‐sildenafil combination (NS‐0200) vs placebo in patients with non‐alcoholic fatty liver disease
por: Chalasani, N., et al.
Publicado: (2018)

Development of highly effective LCB1-based lipopeptides targeting the spike receptor-binding motif of SARS-CoV-2
por: Zhu, Yuanmei, et al.
Publicado: (2023)

Compte rendu de la seance d'etude sur la machine du 1er Octobre 1968 21.00 - 02.00
por: Lefevre, P, et al.
Publicado: (1968)

Fpk1/2 kinases regulate cellular sphingoid long-chain base abundance and alter cellular resistance to LCB elevation or depletion
por: Yamane-Sando, Yukari, et al.
Publicado: (2014)

Cloning, expression and characterization of serine palmitoyltransferase (SPT)-like gene subunit (LCB2) from marine Emiliania huxleyi virus (Coccolithovirus)
por: Liu, Xuhong, et al.
Publicado: (2012)

Resistance profile and mechanism of severe acute respiratory syndrome coronavirus-2 variants to LCB1 inhibitor targeting the spike receptor-binding motif
por: Wu, Tong, et al.
Publicado: (2022)

Overexpression of a ceramide synthase gene,GhCS1, inhibits fiber cell initiation and elongation by promoting the synthesis of ceramides containing dihydroxy LCB and VLCFA
por: Li, Guiming, et al.
Publicado: (2022)

Run 39 - 19th March 1971 - 20.00 - 02.00h: Test of Automatic Beam Dumping when Forcing a PPS Access Door to the ISR Tunnel
por: Gröbner, Oswald, et al.
Publicado: (1971)

In vitro and in vivo activity of GT-1, a novel siderophore cephalosporin, and GT-055, a broad-spectrum β-lactamase inhibitor, against biothreat and ESKAPE pathogens
por: Halasohoris, Stephanie A., et al.
Publicado: (2021)

Two LcbHLH Transcription Factors Interacting with LcMYB1 in Regulating Late Structural Genes of Anthocyanin Biosynthesis in Nicotiana and Litchi chinensis During Anthocyanin Accumulation
por: Lai, Biao, et al.
Publicado: (2016)

Adjustment of Modified Carbapenem Inactivation Method Conditions for Rapid Detection of Carbapenemase-Producing Acinetobacter baumannii
por: Vu, Thao Nguyen, et al.
Publicado: (2020)

Run 185 - 15/16 June 1972 - 23.00h to 02.00h, Rings 1 and 2 - 22 GeV/c - 20 bunches: Lower B in the even intersection regions
por: Autin, B, et al.
Publicado: (1972)

Run 171 - 17 may 1972 - 23.00 to 02.00h, Rings 1 and 2 - 22 GeV/c - 20 bunches: Beam-beam effects on 3rd order resonances
por: Gourber, J P
Publicado: (1972)

The Pyridoxal 5′-Phosphate (PLP)-Dependent Enzyme Serine Palmitoyltransferase (SPT): Effects of the Small Subunits and Insights from Bacterial Mimics of Human hLCB2a HSAN1 Mutations
por: Beattie, Ashley E., et al.
Publicado: (2013)

Panel strain of Klebsiella pneumoniae for beta-lactam antibiotic evaluation: their phenotypic and genotypic characterization
por: Dsouza, Roshan, et al.
Publicado: (2017)

Pharmacokinetic and Pharmacodynamic Profiles of Cefiderocol, a Novel Siderophore Cephalosporin
por: Katsube, Takayuki, et al.
Publicado: (2019)

Cefiderocol: A Novel Siderophore Cephalosporin Defeating Carbapenem-resistant Pathogens
por: Bonomo, Robert A
Publicado: (2019)

Cefiderocol: Discovery, Chemistry, and In Vivo Profiles of a Novel Siderophore Cephalosporin
por: Sato, Takafumi, et al.
Publicado: (2019)

Phenotypic and Genotypic Characterization of Acinetobacter spp. Panel Strains: A Cornerstone to Facilitate Antimicrobial Development
por: D'Souza, Roshan, et al.
Publicado: (2019)

Intrapulmonary pharmacokinetics of cefiderocol, a novel siderophore cephalosporin, in healthy adult subjects
por: Katsube, Takayuki, et al.
Publicado: (2019)

Imaging bacteria with radiolabelled quinolones, cephalosporins and siderophores for imaging infection: a systematic review
por: Auletta, S., et al.
Publicado: (2016)

Education: The role of the first siderophore cephalosporin Fetcroja(®) (cefiderocol) in UK clinical practice: introduction
por: Hussain, Abid
Publicado: (2021)

Urinary tract infection caused by a small colony variant form of capnophilic Escherichia coli leading to misidentification and non-reactions in antimicrobial susceptibility tests
por: Park, Yu Jin, et al.
Publicado: (2018)

In Vitro Antibacterial Properties of Cefiderocol, a Novel Siderophore Cephalosporin, against Gram-Negative Bacteria
por: Ito, Akinobu, et al.
Publicado: (2017)

252 S-649266, a Novel Siderophore Cephalosporin: In vitro activity against Gram-negative bacteria
por: Tsuji, Masakatsu, et al.
Publicado: (2014)

256 S-649266, a Novel Siderophore Cephalosporin: Mechanisms of enhanced activity and beta-lactamase stability
por: Tsuji, Masakatsu, et al.
Publicado: (2014)

In Vitro Activity of Cefiderocol, a Siderophore Cephalosporin, against Multidrug-Resistant Gram-Negative Bacteria
por: Mushtaq, Shazad, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_rad32l9kkdvpeprk8pi0n24dld