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CD80 Expression on Tumor Cells Alters Tumor Microenvironment and Efficacy of Cancer Immunotherapy by CTLA-4 Blockade
SIMPLE SUMMARY: The recent discovery of immune checkpoint inhibitors constituted a breakthrough in cancer treatment, but most patients are resistant to this therapy. Although the co-stimulatory molecule cluster of differentiation (CD) 80 has been detected in several types of tumor cells, its role in...
Autores principales: | Vackova, Julie, Polakova, Ingrid, Johari, Shweta Dilip, Smahel, Michal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072777/ https://www.ncbi.nlm.nih.gov/pubmed/33923750 http://dx.doi.org/10.3390/cancers13081935 |
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