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Risk factors of contrast-induced nephropathy after percutaneous coronary intervention: a retrospective analysis

OBJECTIVE: Contrast-induced nephropathy (CIN) is a serious complication in patients with acute coronary syndrome (ACS) and percutaneous coronary intervention (PCI). This study aimed to analyze the potential risk factors for CIN in patients undergoing PCI. METHODS: Patients with ACS who underwent PCI...

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Autores principales: Wang, Jing, Zhang, Chunyu, Liu, Zhina, Bai, Yanping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072857/
https://www.ncbi.nlm.nih.gov/pubmed/33878914
http://dx.doi.org/10.1177/03000605211005972
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author Wang, Jing
Zhang, Chunyu
Liu, Zhina
Bai, Yanping
author_facet Wang, Jing
Zhang, Chunyu
Liu, Zhina
Bai, Yanping
author_sort Wang, Jing
collection PubMed
description OBJECTIVE: Contrast-induced nephropathy (CIN) is a serious complication in patients with acute coronary syndrome (ACS) and percutaneous coronary intervention (PCI). This study aimed to analyze the potential risk factors for CIN in patients undergoing PCI. METHODS: Patients with ACS who underwent PCI treatment from January 2017 to January 2020 were selected. The patients’ characteristics and medical information were collected and compared. RESULTS: A total of 1331 patients undergoing PCI were included. The incidence of CIN was 15.33%. Logistic regression analyses showed that a left ventricular ejection fraction ≤45% (odds ratio [OR] 4.18, 95% confidence interval [CI] 1.10–7.36), serum creatinine levels ≤60 μmol/L (OR 3.03, 95% CI 1.21–5.57), age ≥65 years (OR 2.75, 95% CI 1.32–4.60), log N-terminal pro-B-type natriuretic peptide levels ≥2.5 pg/mL (OR 2.31, 95% CI 1.18–5.13), uric acid levels ≥350 μmol/L (OR 2.29, 95% CI 1.04–5.30), emergency percutaneous intervention (OR 1.35, 95% CI 0.34–3.12), and triglyceride levels ≤1.30 mmol/L (OR 1.10, 95% CI 0.01–2.27) were independent risk factors for CIN in patients who underwent PCI. CONCLUSIONS: Early prevention is required to reduce the occurrence of CIN in patients who undergo PCI and have risk factors for CIN.
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spelling pubmed-80728572021-05-13 Risk factors of contrast-induced nephropathy after percutaneous coronary intervention: a retrospective analysis Wang, Jing Zhang, Chunyu Liu, Zhina Bai, Yanping J Int Med Res Retrospective Clinical Research Report OBJECTIVE: Contrast-induced nephropathy (CIN) is a serious complication in patients with acute coronary syndrome (ACS) and percutaneous coronary intervention (PCI). This study aimed to analyze the potential risk factors for CIN in patients undergoing PCI. METHODS: Patients with ACS who underwent PCI treatment from January 2017 to January 2020 were selected. The patients’ characteristics and medical information were collected and compared. RESULTS: A total of 1331 patients undergoing PCI were included. The incidence of CIN was 15.33%. Logistic regression analyses showed that a left ventricular ejection fraction ≤45% (odds ratio [OR] 4.18, 95% confidence interval [CI] 1.10–7.36), serum creatinine levels ≤60 μmol/L (OR 3.03, 95% CI 1.21–5.57), age ≥65 years (OR 2.75, 95% CI 1.32–4.60), log N-terminal pro-B-type natriuretic peptide levels ≥2.5 pg/mL (OR 2.31, 95% CI 1.18–5.13), uric acid levels ≥350 μmol/L (OR 2.29, 95% CI 1.04–5.30), emergency percutaneous intervention (OR 1.35, 95% CI 0.34–3.12), and triglyceride levels ≤1.30 mmol/L (OR 1.10, 95% CI 0.01–2.27) were independent risk factors for CIN in patients who underwent PCI. CONCLUSIONS: Early prevention is required to reduce the occurrence of CIN in patients who undergo PCI and have risk factors for CIN. SAGE Publications 2021-04-20 /pmc/articles/PMC8072857/ /pubmed/33878914 http://dx.doi.org/10.1177/03000605211005972 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Retrospective Clinical Research Report
Wang, Jing
Zhang, Chunyu
Liu, Zhina
Bai, Yanping
Risk factors of contrast-induced nephropathy after percutaneous coronary intervention: a retrospective analysis
title Risk factors of contrast-induced nephropathy after percutaneous coronary intervention: a retrospective analysis
title_full Risk factors of contrast-induced nephropathy after percutaneous coronary intervention: a retrospective analysis
title_fullStr Risk factors of contrast-induced nephropathy after percutaneous coronary intervention: a retrospective analysis
title_full_unstemmed Risk factors of contrast-induced nephropathy after percutaneous coronary intervention: a retrospective analysis
title_short Risk factors of contrast-induced nephropathy after percutaneous coronary intervention: a retrospective analysis
title_sort risk factors of contrast-induced nephropathy after percutaneous coronary intervention: a retrospective analysis
topic Retrospective Clinical Research Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072857/
https://www.ncbi.nlm.nih.gov/pubmed/33878914
http://dx.doi.org/10.1177/03000605211005972
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