KRAS/LKB1 and KRAS/TP53 co-mutations create divergent immune signatures in lung adenocarcinomas

Lung adenocarcinomas exhibit various patterns of genomic alterations. During the development of this cancer, KRAS serves as a driver oncogene with a relatively high mutational frequency. Emerging data suggest that lung adenocarcinomas with KRAS mutations can show enhanced PD-L1 expression and additi...

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Detalles Bibliográficos
Autores principales: Gu, Meichen, Xu, Tiankai, Chang, Pengyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072935/
https://www.ncbi.nlm.nih.gov/pubmed/33995590
http://dx.doi.org/10.1177/17588359211006950

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072935/
https://www.ncbi.nlm.nih.gov/pubmed/33995590
http://dx.doi.org/10.1177/17588359211006950

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