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Spurious regulatory connections dictate the expression‐fitness landscape of translation factors

During steady‐state cell growth, individual enzymatic fluxes can be directly inferred from growth rate by mass conservation, but the inverse problem remains unsolved. Perturbing the flux and expression of a single enzyme could have pleiotropic effects that may or may not dominate the impact on cell...

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Detalles Bibliográficos
Autores principales: Lalanne, Jean‐Benoît, Parker, Darren J, Li, Gene‐Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073009/
https://www.ncbi.nlm.nih.gov/pubmed/33900014
http://dx.doi.org/10.15252/msb.202110302