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Spurious regulatory connections dictate the expression‐fitness landscape of translation factors
During steady‐state cell growth, individual enzymatic fluxes can be directly inferred from growth rate by mass conservation, but the inverse problem remains unsolved. Perturbing the flux and expression of a single enzyme could have pleiotropic effects that may or may not dominate the impact on cell...
Autores principales: | Lalanne, Jean‐Benoît, Parker, Darren J, Li, Gene‐Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073009/ https://www.ncbi.nlm.nih.gov/pubmed/33900014 http://dx.doi.org/10.15252/msb.202110302 |
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