Cargando…

The epithelial–mesenchymal transition regulators Twist, Slug, and Snail are associated with aggressive tumour features and poor outcome in prostate cancer patients

The prognostic importance of transcription factors promoting epithelial–mesenchymal transition (EMT) and angiogenesis has not been well explored in prostate cancer patients with long follow‐up, nor the interplay between these factors. The objective of this study was to assess the individual protein...

Descripción completa

Detalles Bibliográficos
Autores principales:	Børretzen, Astrid, Gravdal, Karsten, Haukaas, Svein A, Mannelqvist, Monica, Beisland, Christian, Akslen, Lars A, Halvorsen, Ole J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073012/ https://www.ncbi.nlm.nih.gov/pubmed/33605548 http://dx.doi.org/10.1002/cjp2.202

Ejemplares similares

FOXC2 expression and epithelial–mesenchymal phenotypes are associated with castration resistance, metastasis and survival in prostate cancer
por: Børretzen, Astrid, et al.
Publicado: (2019)

Microvascular proliferation is associated with high tumour blood flow by mpMRI and disease progression in primary prostate cancer
por: Børretzen, Astrid, et al.
Publicado: (2023)

A positive Real-Time Elastography (RTE) combined with a Prostate Cancer Gene 3 (PCA3) score above 35 convey a high probability of intermediate- or high-risk prostate cancer in patient admitted for primary prostate biopsy
por: Nygård, Yngve, et al.
Publicado: (2016)

Optimising preoperative risk stratification tools for prostate cancer using mpMRI
por: Reisæter, Lars A. R., et al.
Publicado: (2017)

Expression of transcription factors snail, slug, and twist in human bladder carcinoma
por: Yu, Qinchao, et al.
Publicado: (2010)

Expression of Twist, Slug and Snail in esophageal squamous cell carcinoma and their prognostic significance
por: Xu, Shanshan, et al.
Publicado: (2021)

The F-box protein Ppa is a common regulator of core EMT factors Twist, Snail, Slug, and Sip1
por: Lander, Rachel, et al.
Publicado: (2011)

Inhibition of Migration, Invasion and Drug Resistance of Pancreatic Adenocarcinoma Cells – Role of Snail, Slug and Twist and Small Molecule Inhibitors
por: Kaşıkcı, Ezgi, et al.
Publicado: (2020)

An 18-Gene Signature for Vascular Invasion Is Associated with Aggressive Features and Reduced Survival in Breast Cancer
por: Mannelqvist, Monica, et al.
Publicado: (2014)

Inhibition of Migration, Invasion and Drug Resistance of Pancreatic Adenocarcinoma Cells – Role of Snail, Slug and Twist and Small Molecule Inhibitors [Corrigendum]
Publicado: (2022)

Biological activities of gastropods secretions: snail and slug slime
por: Rashad, Muhammad, et al.
Publicado: (2023)

PRSS2 remodels the tumor microenvironment via repression of Tsp1 to stimulate tumor growth and progression
por: Sui, Lufei, et al.
Publicado: (2022)

Slug, Twist, and E-Cadherin as Immunohistochemical Biomarkers in Meningeal Tumors
por: Nagaishi, Masaya, et al.
Publicado: (2012)

Reciprocal expression of Slug and Snail in human oral cancer cells
por: Nakamura, Ryosuke, et al.
Publicado: (2018)

Experimental indications of gardeners’ anecdotes that snails interfere with invasive slugs
por: Dörler, Daniel, et al.
Publicado: (2021)

Cordycepin Inhibits Triple-Negative Breast Cancer Cell Migration and Invasion by Regulating EMT-TFs SLUG, TWIST1, SNAIL1, and ZEB1
por: Wei, Chunli, et al.
Publicado: (2022)

Ringiculid bubble snails recovered as the sister group to sea slugs (Nudipleura)
por: Kano, Yasunori, et al.
Publicado: (2016)

SLUG and SNAIL as Potential Immunohistochemical Biomarkers for Renal Cancer Staging and Survival
por: Zivotic, Maja, et al.
Publicado: (2023)

AP-2β inhibits hepatocellular carcinoma invasion and metastasis through Slug and Snail to suppress epithelial-mesenchymal transition
por: Yang, Liu, et al.
Publicado: (2018)

Targeting the SPOCK1-snail/slug axis-mediated epithelial-to-mesenchymal transition by apigenin contributes to repression of prostate cancer metastasis
por: Chien, Ming-Hsien, et al.
Publicado: (2019)

EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer
por: Haslehurst, Alexandria M, et al.
Publicado: (2012)

The Hedgehog/GLI signaling pathway activates transcription of Slug (Snail2) in melanoma cells
por: Horák, Pavel, et al.
Publicado: (2023)

Elf5 inhibits epithelial mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2/Slug
por: Chakrabarti, Rumela, et al.
Publicado: (2012)

MiR-22 suppresses epithelial–mesenchymal transition in bladder cancer by inhibiting Snail and MAPK1/Slug/vimentin feedback loop
por: Xu, Mingjie, et al.
Publicado: (2018)

Glucocorticoids ameliorate TGF-β1-mediated epithelial-to-mesenchymal transition of airway epithelium through MAPK and Snail/Slug signaling pathways
por: Yang, Hyun-Woo, et al.
Publicado: (2017)

Lipocalin 2 expression is associated with aggressive features of endometrial cancer
por: Mannelqvist, Monica, et al.
Publicado: (2012)

Relevance and prognostic ability of Twist, Slug and tumor spread through air spaces in lung adenocarcinoma
por: Liu, Ao, et al.
Publicado: (2020)

Pericytes/vessel-associated mural cells (VAMCs) are the major source of key epithelial-mesenchymal transition (EMT) factors SLUG and TWIST in human glioma
por: Mäder, Lisa, et al.
Publicado: (2018)

Snail/Slug-YAP/TAZ Complexes Control Skeletal Stem Cell Self-Renewal and Differentiation
por: Tang, Yi, et al.
Publicado: (2016)

Fermenting Bread Dough as a Cheap, Effective, Nontoxic, and Generic Attractant for Pest Snails and Slugs
por: Veasey, Robin, et al.
Publicado: (2021)

Origin and significance of two pairs of head tentacles in the radiation of euthyneuran sea slugs and land snails
por: Brenzinger, Bastian, et al.
Publicado: (2021)

Copper depletion inhibits CoCl(2)-induced aggressive phenotype of MCF-7 cells via downregulation of HIF-1 and inhibition of Snail/Twist-mediated epithelial-mesenchymal transition
por: Li, Shun, et al.
Publicado: (2015)

DDX39 Overexpression Predicts a Poor Prognosis and Promotes Aggressiveness of Melanoma by Cooperating With SNAIL
por: Xing, Chengjuan, et al.
Publicado: (2020)

Microvascular proliferation is associated with aggressive tumour features and reduced survival in lung adenocarcinoma
por: Ramnefjell, Maria, et al.
Publicado: (2017)

Proteoglycan SPOCK1 as a Poor Prognostic Marker Promotes Malignant Progression of Clear Cell Renal Cell Carcinoma via Triggering the Snail/Slug-MMP-2 Axis-Mediated Epithelial-to-Mesenchymal Transition
por: Lin, Yung-Wei, et al.
Publicado: (2023)

Down‐regulation of microRNAs of the miR‐200 family and up‐regulation of Snail and Slug in inflammatory bowel diseases — hallmark of epithelial−mesenchymal transition
por: Zidar, Nina, et al.
Publicado: (2016)

Stabilization of the transcription factors slug and twist by the deubiquitinase dub3 is a key requirement for tumor metastasis
por: Lin, Yiwei, et al.
Publicado: (2017)

The Transcription Factors Snail and Slug Activate the Transforming Growth Factor-Beta Signaling Pathway in Breast Cancer
por: Dhasarathy, Archana, et al.
Publicado: (2011)

Land snails and slugs of Bau limestone hills, Sarawak (Malaysia, Borneo), with the descriptions of 13 new species
por: Marzuki, Mohammad Effendi bin, et al.
Publicado: (2021)

Down-regulation of miR-129-5p via the Twist1-Snail feedback loop stimulates the epithelial-mesenchymal transition and is associated with poor prognosis in breast cancer
por: Yu, Yue, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_sub5osraeji1lbahqmp3v819lv