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The Challenging Diagnosis of Pediatric Multisystem Inflammatory Syndrome Associated with Sars-Cov-2 Infection-Two Case Reports and Literature Review

Severe acute respiratory coronavirus 2 (SARS-CoV-2) is a novel coronavirus discovered in 2019 that caused the coronavirus disease 2019 (COVID19). During the last year, over 70 million people were infected and more than 1.5 million people died. Despite the tremendous number of people infected, childr...

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Autores principales: Ionescu, Marcela Daniela, Taras, Roxana, Dombici, Bianca, Balgradean, Mihaela, Berghea, Elena Camelia, Nicolescu, Alin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073032/
https://www.ncbi.nlm.nih.gov/pubmed/33921718
http://dx.doi.org/10.3390/jpm11040318
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author Ionescu, Marcela Daniela
Taras, Roxana
Dombici, Bianca
Balgradean, Mihaela
Berghea, Elena Camelia
Nicolescu, Alin
author_facet Ionescu, Marcela Daniela
Taras, Roxana
Dombici, Bianca
Balgradean, Mihaela
Berghea, Elena Camelia
Nicolescu, Alin
author_sort Ionescu, Marcela Daniela
collection PubMed
description Severe acute respiratory coronavirus 2 (SARS-CoV-2) is a novel coronavirus discovered in 2019 that caused the coronavirus disease 2019 (COVID19). During the last year, over 70 million people were infected and more than 1.5 million people died. Despite the tremendous number of people infected, children were less affected and presented milder forms of the disease. A short time after the pandemic was declared, a new hyperinflammatory syndrome resembling Kawasaki disease (KD) was described in children with confirmed or suspected SARS-CoV-2 infection named multisystem inflammatory syndrome in children (MIS-C). The incidence of MIS-C is low and it has a polymorphous clinical presentation, making the diagnosis difficult. Although the incidence is reduced, there is a high risk of cardiovascular complications. In order to raise awareness, we present the cases of two pediatric patients diagnosed with MIS-C in our clinic.
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spelling pubmed-80730322021-04-27 The Challenging Diagnosis of Pediatric Multisystem Inflammatory Syndrome Associated with Sars-Cov-2 Infection-Two Case Reports and Literature Review Ionescu, Marcela Daniela Taras, Roxana Dombici, Bianca Balgradean, Mihaela Berghea, Elena Camelia Nicolescu, Alin J Pers Med Article Severe acute respiratory coronavirus 2 (SARS-CoV-2) is a novel coronavirus discovered in 2019 that caused the coronavirus disease 2019 (COVID19). During the last year, over 70 million people were infected and more than 1.5 million people died. Despite the tremendous number of people infected, children were less affected and presented milder forms of the disease. A short time after the pandemic was declared, a new hyperinflammatory syndrome resembling Kawasaki disease (KD) was described in children with confirmed or suspected SARS-CoV-2 infection named multisystem inflammatory syndrome in children (MIS-C). The incidence of MIS-C is low and it has a polymorphous clinical presentation, making the diagnosis difficult. Although the incidence is reduced, there is a high risk of cardiovascular complications. In order to raise awareness, we present the cases of two pediatric patients diagnosed with MIS-C in our clinic. MDPI 2021-04-19 /pmc/articles/PMC8073032/ /pubmed/33921718 http://dx.doi.org/10.3390/jpm11040318 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ionescu, Marcela Daniela
Taras, Roxana
Dombici, Bianca
Balgradean, Mihaela
Berghea, Elena Camelia
Nicolescu, Alin
The Challenging Diagnosis of Pediatric Multisystem Inflammatory Syndrome Associated with Sars-Cov-2 Infection-Two Case Reports and Literature Review
title The Challenging Diagnosis of Pediatric Multisystem Inflammatory Syndrome Associated with Sars-Cov-2 Infection-Two Case Reports and Literature Review
title_full The Challenging Diagnosis of Pediatric Multisystem Inflammatory Syndrome Associated with Sars-Cov-2 Infection-Two Case Reports and Literature Review
title_fullStr The Challenging Diagnosis of Pediatric Multisystem Inflammatory Syndrome Associated with Sars-Cov-2 Infection-Two Case Reports and Literature Review
title_full_unstemmed The Challenging Diagnosis of Pediatric Multisystem Inflammatory Syndrome Associated with Sars-Cov-2 Infection-Two Case Reports and Literature Review
title_short The Challenging Diagnosis of Pediatric Multisystem Inflammatory Syndrome Associated with Sars-Cov-2 Infection-Two Case Reports and Literature Review
title_sort challenging diagnosis of pediatric multisystem inflammatory syndrome associated with sars-cov-2 infection-two case reports and literature review
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073032/
https://www.ncbi.nlm.nih.gov/pubmed/33921718
http://dx.doi.org/10.3390/jpm11040318
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