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Fully Automated Synthesis of Novel TSPO PET Imaging Ligand [(18)F]Fluoroethyltemazepam
Introduction: Benzodiazepines, including temazepam are described as TSPO antagonists. In fact, TSPO was initially described as a peripheral benzodiazepine receptor (PBR) with a secondary binding site for diazepam. TSPO is a potential imaging target of neuroinflammation because there is an amplificat...
Autores principales: | Fiorenza, Dario, Nicolai, Emanuele, Cavaliere, Carlo, Fiorino, Ferdinando, Esposito, Giovanna, Salvatore, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073130/ https://www.ncbi.nlm.nih.gov/pubmed/33921765 http://dx.doi.org/10.3390/molecules26082372 |
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