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Quinazoline Derivatives Designed as Efflux Pump Inhibitors: Molecular Modeling and Spectroscopic Studies

Multidrug resistance of bacteria is a worrying concern in the therapeutic field and an alternative method to combat it is designing new efflux pump inhibitors (EPIs). This article presents a molecular study of two quinazoline derivatives, labelled BG1189 and BG1190, proposed as EPIs. In silico appro...

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Detalles Bibliográficos
Autores principales: Udrea, Ana-Maria, Dinache, Andra, Pagès, Jean-Marie, Pirvulescu, Ruxandra Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073189/
https://www.ncbi.nlm.nih.gov/pubmed/33921798
http://dx.doi.org/10.3390/molecules26082374