Synthesis and Single Crystal Structures of N-Substituted Benzamides and Their Chemoselective Selenation/Reduction Derivatives

A series of N-aryl-N-(2-oxo-2-arylethyl) benzamides and cinnamides has been prepared. The reaction of the benzamides with Woollins’ reagent, a highly efficient chemoselective selenation/reduction reagent, gave the corresponding N-aryl-N-(arylenethyl) benzoselenoamides in good yields. Five representa...

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Autores principales: Hua, Guoxiong, Carpenter-Warren, Cameron L., Cordes, David B., Slawin, Alexandra M. Z., Woollins, J. Derek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073290/
https://www.ncbi.nlm.nih.gov/pubmed/33921716
http://dx.doi.org/10.3390/molecules26082367
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author Hua, Guoxiong
Carpenter-Warren, Cameron L.
Cordes, David B.
Slawin, Alexandra M. Z.
Woollins, J. Derek
author_facet Hua, Guoxiong
Carpenter-Warren, Cameron L.
Cordes, David B.
Slawin, Alexandra M. Z.
Woollins, J. Derek
author_sort Hua, Guoxiong
collection PubMed
description A series of N-aryl-N-(2-oxo-2-arylethyl) benzamides and cinnamides has been prepared. The reaction of the benzamides with Woollins’ reagent, a highly efficient chemoselective selenation/reduction reagent, gave the corresponding N-aryl-N-(arylenethyl) benzoselenoamides in good yields. Five representative single crystal X-ray structures are discussed.
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spelling pubmed-80732902021-04-27 Synthesis and Single Crystal Structures of N-Substituted Benzamides and Their Chemoselective Selenation/Reduction Derivatives Hua, Guoxiong Carpenter-Warren, Cameron L. Cordes, David B. Slawin, Alexandra M. Z. Woollins, J. Derek Molecules Article A series of N-aryl-N-(2-oxo-2-arylethyl) benzamides and cinnamides has been prepared. The reaction of the benzamides with Woollins’ reagent, a highly efficient chemoselective selenation/reduction reagent, gave the corresponding N-aryl-N-(arylenethyl) benzoselenoamides in good yields. Five representative single crystal X-ray structures are discussed. MDPI 2021-04-19 /pmc/articles/PMC8073290/ /pubmed/33921716 http://dx.doi.org/10.3390/molecules26082367 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hua, Guoxiong
Carpenter-Warren, Cameron L.
Cordes, David B.
Slawin, Alexandra M. Z.
Woollins, J. Derek
Synthesis and Single Crystal Structures of N-Substituted Benzamides and Their Chemoselective Selenation/Reduction Derivatives
title Synthesis and Single Crystal Structures of N-Substituted Benzamides and Their Chemoselective Selenation/Reduction Derivatives
title_full Synthesis and Single Crystal Structures of N-Substituted Benzamides and Their Chemoselective Selenation/Reduction Derivatives
title_fullStr Synthesis and Single Crystal Structures of N-Substituted Benzamides and Their Chemoselective Selenation/Reduction Derivatives
title_full_unstemmed Synthesis and Single Crystal Structures of N-Substituted Benzamides and Their Chemoselective Selenation/Reduction Derivatives
title_short Synthesis and Single Crystal Structures of N-Substituted Benzamides and Their Chemoselective Selenation/Reduction Derivatives
title_sort synthesis and single crystal structures of n-substituted benzamides and their chemoselective selenation/reduction derivatives
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073290/
https://www.ncbi.nlm.nih.gov/pubmed/33921716
http://dx.doi.org/10.3390/molecules26082367
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