High-Efficacy α,β-Dehydromonacolin S Improves Hepatic Steatosis and Suppresses Gluconeogenesis Pathway in High-Fat Diet-Induced Obese Rats

Isolated α,β-dehydromonacolin S (C5) from soil-derived fungus Aspergillus sclerotiorum PSU-RSPG178 was recently shown to exhibit an inhibitory effect against 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) activity in vitro. In this study, we investigated the effects of C5 on lipid-lowering,...

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Detalles Bibliográficos
Autores principales: Kaewmalee, Jutatip, Ontawong, Atcharaporn, Duangjai, Acharaporn, Tansakul, Chittreeya, Rukachaisirikul, Vatcharin, Muanprasat, Chatchai, Srimaroeng, Chutima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073358/
https://www.ncbi.nlm.nih.gov/pubmed/33920678
http://dx.doi.org/10.3390/ph14040375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073358/
https://www.ncbi.nlm.nih.gov/pubmed/33920678
http://dx.doi.org/10.3390/ph14040375

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