Cargando…

Impact of Age and Comorbidity on Multimodal Management and Survival from Colorectal Cancer: A Population-Based Study

This retrospective population-based study examined the impact of age and comorbidity burden on multimodal management and survival from colorectal cancer (CRC). From 2000 to 2015, 1479 consecutive patients, who underwent surgical resection for CRC, were reviewed for age-adjusted Charlson comorbidity...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kellokumpu, Ilmo, Kairaluoma, Matti, Mecklin, Jukka-Pekka, Kellokumpu, Henrik, Väyrynen, Ville, Wirta, Erkki-Ville, Sihvo, Eero, Kuopio, Teijo, Seppälä, Toni T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073362/ https://www.ncbi.nlm.nih.gov/pubmed/33920665 http://dx.doi.org/10.3390/jcm10081751

Ejemplares similares

Immune Contexture of MMR-Proficient Primary Colorectal Cancer and Matched Liver and Lung Metastases
por: Ahtiainen, Maarit, et al.
Publicado: (2021)

Immunoscore in mismatch repair‐proficient and ‐deficient colon cancer
por: Wirta, Erkki‐Ville, et al.
Publicado: (2017)

Tertiary lymphoid structures in pulmonary metastases of microsatellite stable colorectal cancer
por: Karjula, Topias, et al.
Publicado: (2023)

CD3(+) and CD8(+) T-Cell-Based Immune Cell Score and PD-(L)1 Expression in Pulmonary Metastases of Microsatellite Stable Colorectal Cancer
por: Karjula, Topias, et al.
Publicado: (2022)

Incidence and management of patients with colorectal cancer and synchronous and metachronous colorectal metastases: a population‐based study
por: Väyrynen, V., et al.
Publicado: (2020)

Spatially resolved multimarker evaluation of CD274 (PD-L1)/PDCD1 (PD-1) immune checkpoint expression and macrophage polarisation in colorectal cancer
por: Elomaa, Hanna, et al.
Publicado: (2023)

Prognostic significance of spatial and density analysis of T lymphocytes in colorectal cancer
por: Elomaa, Hanna, et al.
Publicado: (2022)

Immunophenotype based on inflammatory cells, PD-1/PD-L1 signalling pathway and M2 macrophages predicts survival in gastric cancer
por: Junttila, Anna, et al.
Publicado: (2020)

Immunological and prognostic significance of tumour necrosis in colorectal cancer
por: Kastinen, Meeri, et al.
Publicado: (2023)

Laparoscopic Colectomy vs Laparoscopic CME: a Retrospective Study of Two Hospitals with Comparable Laparoscopic Experience
por: Rinne, Juha KA, et al.
Publicado: (2020)

Immunoprofiles and DNA Methylation of Inflammatory Marker Genes in Ulcerative Colitis-Associated Colorectal Tumorigenesis
por: Mäki-Nevala, Satu, et al.
Publicado: (2021)

Combination of microsatellite instability and BRAF mutation status for subtyping colorectal cancer
por: Seppälä, T T, et al.
Publicado: (2015)

Prognostic Value of Immune Environment Analysis in Small Bowel Adenocarcinomas with Verified Mutational Landscape and Predisposing Conditions
por: Wirta, Erkki-Ville, et al.
Publicado: (2020)

Stromal hyaluronan accumulation is associated with low immune response and poor prognosis in pancreatic cancer
por: Tahkola, Kyösti, et al.
Publicado: (2021)

Exome and immune cell score analyses reveal great variation within synchronous primary colorectal cancers
por: Hänninen, Ulrika A., et al.
Publicado: (2019)

Prognostic impact of CD73 expression and its relationship to PD-L1 in patients with radically treated pancreatic cancer
por: Tahkola, Kyösti, et al.
Publicado: (2020)

Does breast carcinoma belong to the Lynch syndrome tumor spectrum? – Somatic mutational profiles vs. ovarian and colorectal carcinomas
por: Porkka, Noora K., et al.
Publicado: (2020)

Systemic circulating microRNA landscape in Lynch syndrome
por: Sievänen, Tero, et al.
Publicado: (2022)

Domain-specific transfer learning in the automated scoring of tumor-stroma ratio from histopathological images of colorectal cancer
por: Petäinen, Liisa, et al.
Publicado: (2023)

Implementation of Multimodality Therapy and Minimally Invasive Surgery: Short- and Long-term Outcomes of Gastric Cancer Surgery in Medium-Volume Center
por: Junttila, Anna, et al.
Publicado: (2022)

Uptake of genetic testing by the children of Lynch syndrome variant carriers across three generations
por: Seppälä, Toni T, et al.
Publicado: (2017)

Clinical characteristics of pancreatic and biliary tract cancers in Lynch syndrome: A retrospective analysis from the Finnish National Lynch Syndrome Research Registry
por: Zalevskaja, Kristina, et al.
Publicado: (2023)

Predictive value of p53, Ki67 and TLR5 in neoplastic progression of Barrett’s esophagus: a matched case–control study
por: Helminen, Olli, et al.
Publicado: (2022)

Cost-analysis and effectiveness of one-stage laparoscopic versus two-stage endolaparoscopic management of cholecystocholedocholithiasis: a retrospective cohort study
por: Mattila, Anne, et al.
Publicado: (2017)

Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival
por: Cajuso, Tatiana, et al.
Publicado: (2019)

Identification of glycoproteins expressing tumour-associated PNA-binding sites in colorectal carcinomas by SDS-GEL electrophoresis and PNA-labelling.
por: Kellokumpu, I., et al.
Publicado: (1987)

Immune cell score in pancreatic cancer—comparison of hotspot and whole-section techniques
por: Tahkola, Kyösti, et al.
Publicado: (2019)

Descriptive study on subjective experience of genetic testing with respect to relationship, family planning and psychosocial wellbeing among women with lynch syndrome
por: Kalamo, Mari, et al.
Publicado: (2021)

Both comorbidity and worse performance status are associated with poorer overall survival after external beam radiotherapy for prostate cancer
por: Lehtonen, Miikka, et al.
Publicado: (2020)

Improved accuracy in colorectal cancer tissue decomposition through refinement of established deep learning solutions
por: Prezja, Fabi, et al.
Publicado: (2023)

Breast carcinoma and Lynch syndrome: molecular analysis of tumors arising in mutation carriers, non-carriers, and sporadic cases
por: Lotsari, Johanna E, et al.
Publicado: (2012)

Golgi pH, Ion and Redox Homeostasis: How Much Do They Really Matter?
por: Kellokumpu, Sakari
Publicado: (2019)

Radiotherapy-induced diffuse myocardial fibrosis in early-stage breast cancer patients – multimodality imaging study with six-year follow-up
por: Moisander, Mikko, et al.
Publicado: (2023)

Body Weight, Physical Activity, and Risk of Cancer in Lynch Syndrome
por: Sievänen, Tero, et al.
Publicado: (2021)

Ex vivo modelling of drug efficacy in a rare metastatic urachal carcinoma
por: Mäkelä, Rami, et al.
Publicado: (2020)

High-Frequency Electroencephalographic Activity in Left Temporal Area Is Associated with Pleasant Emotion Induced by Video Clips
por: Kortelainen, Jukka, et al.
Publicado: (2015)

Contribution of smoking change to 45-year trend in prevalence of chronic bronchitis in Finland
por: Vartiainen, Ville A, et al.
Publicado: (2022)

Ex vivo assessment of targeted therapies in a rare metastatic epithelial–myoepithelial carcinoma
por: Mäkelä, Rami, et al.
Publicado: (2020)

Influence of Sampling Practices on the Appearance of DNA Image Histograms of Prostate Cells in FNAB Samples
por: Buhmeida, Abdelbaset, et al.
Publicado: (1999)

Transcripts of the Prostate Cancer-Associated Gene ANO7 Are Retained in the Nuclei of Prostatic Epithelial Cells
por: Metsälä, Olli, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_mo0gelvg817gmo011ator1u6hu