The Role of Heparan Sulfate and Neuropilin 2 in VEGFA Signaling in Human Endothelial Tip Cells and Non-Tip Cells during Angiogenesis In Vitro

During angiogenesis, vascular endothelial growth factor A (VEGFA) regulates endothelial cell (EC) survival, tip cell formation, and stalk cell proliferation via VEGF receptor 2 (VEGFR2). VEGFR2 can interact with VEGFR2 co-receptors such as heparan sulfate proteoglycans (HSPGs) and neuropilin 2 (NRP2...

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Detalles Bibliográficos
Autores principales: Dallinga, Marchien G., Habani, Yasmin I., Schimmel, Alinda W. M., Dallinga-Thie, Geesje M., van Noorden, Cornelis J. F., Klaassen, Ingeborg, Schlingemann, Reinier O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073389/
https://www.ncbi.nlm.nih.gov/pubmed/33923753
http://dx.doi.org/10.3390/cells10040926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073389/
https://www.ncbi.nlm.nih.gov/pubmed/33923753
http://dx.doi.org/10.3390/cells10040926

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