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The Expression Regulation and Biological Function of Autotaxin

Autotaxin (ATX) is a secreted glycoprotein and functions as a key enzyme to produce extracellular lysophosphatidic acid (LPA). LPA interacts with at least six G protein-coupled receptors, LPAR1-6, on the cell membrane to activate various signal transduction pathways through distinct G proteins, such...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaotian, Li, Mengmiao, Yin, Nan, Zhang, Junjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073485/
https://www.ncbi.nlm.nih.gov/pubmed/33921676
http://dx.doi.org/10.3390/cells10040939