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PET Imaging of GPR44 by Antagonist [(11)C]MK-7246 in Pigs

A validated imaging marker for beta-cell mass would improve understanding of diabetes etiology and enable new strategies in therapy development. We previously identified the membrane-spanning protein GPR44 as highly expressed and specific to the beta cells of the pancreas. The selective GPR44 antago...

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Detalles Bibliográficos
Autores principales:	Cheung, Pierre, Zhang, Bo, Puuvuori, Emmi, Estrada, Sergio, Amin, Mohammad A., Ye, Sofie, Korsgren, Olle, Odell, Luke R., Eriksson, Jonas, Eriksson, Olof
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073488/ https://www.ncbi.nlm.nih.gov/pubmed/33923731 http://dx.doi.org/10.3390/biomedicines9040434

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