Cargando…
Activation of the JNK/MAPK Signaling Pathway by TGF-β1 Enhances Neonatal Fc Receptor Expression and IgG Transcytosis
The neonatal Fc receptor (FcRn) transports maternal immunoglobulin G (IgG) to the foetus or newborn and protects the IgG from degradation. FcRn is expressed in several porcine tissues and cell types and its expression levels are regulated by immune and inflammatory events. IPEC-J2 cells are porcine...
Autores principales: | Qian, Shaoju, Li, Chenxi, Liu, Xi, Jia, Xiangchao, Xiao, Yuncai, Li, Zili |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073669/ https://www.ncbi.nlm.nih.gov/pubmed/33923917 http://dx.doi.org/10.3390/microorganisms9040879 |
Ejemplares similares
-
Reduced FcRn-mediated transcytosis of IgG2 due to a missing Glycine in its lower hinge
por: Stapleton, Nigel M., et al.
Publicado: (2019) -
An IgA mimicry of IgG that binds polymeric immunoglobulin receptor for mucosa transcytosis
por: Mao, Changchuin, et al.
Publicado: (2020) -
Neonatal Fc receptor expression in macrophages is indispensable for IgG homeostasis
por: Challa, Dilip K., et al.
Publicado: (2019) -
Characterization of the interactions of rabbit neonatal Fc receptor (FcRn) with rabbit and human IgG isotypes
por: Szikora, Bence, et al.
Publicado: (2017) -
Antigen physiochemical properties allosterically effect the IgG Fc-region and Fc neonatal receptor affinity
por: Sun, Yue, et al.
Publicado: (2020)