Cargando…

The Biological Effects of Forsythia Leaves Containing the Cyclic AMP Phosphodiesterase 4 Inhibitor Phillyrin

Forsythia fruit (Forsythia suspensa Vahl (Oleaceae)) is a common component of Kampo medicines for treating the common cold, influenza, and allergies. The main polyphenolic compounds in the leaves of F. suspensa are pinoresinol β-d-glucoside, phillyrin and forsythiaside, and their levels are higher i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nishibe, Sansei, Mitsui-Saitoh, Kumiko, Sakai, Junichi, Fujikawa, Takahiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073696/ https://www.ncbi.nlm.nih.gov/pubmed/33921630 http://dx.doi.org/10.3390/molecules26082362

Ejemplares similares

The Differences of Mechanisms in Antihypertensive and Anti-Obesity Effects of Eucommia Leaf Extract between Rodents and Humans
por: Nishibe, Sansei, et al.
Publicado: (2023)

The Mechanism of Phillyrin from the Leaves of Forsythia suspensa for Improving Insulin Resistance
por: Xu, Xiaoqing, et al.
Publicado: (2019)

Green Extraction of Forsythoside A, Phillyrin and Phillygenol from Forsythia suspensa Leaves Using a β-Cyclodextrin-Assisted Method
por: Li, Jing, et al.
Publicado: (2022)

Comparative Transcriptome Analysis of MeJA Responsive Enzymes Involved in Phillyrin Biosynthesis of Forsythia suspensa
por: Liu, Xiaoran, et al.
Publicado: (2022)

Cyclic AMP compartments and signaling specificity: Role of cyclic nucleotide phosphodiesterases
por: Conti, Marco, et al.
Publicado: (2014)

Asperuloside stimulates metabolic function in rats across several organs under high-fat diet conditions, acting like the major ingredient of Eucommia leaves with anti-obesity activity
por: Fujikawa, Takahiko, et al.
Publicado: (2012)

Bacterial Cyclic AMP-Phosphodiesterase Activity Coordinates Biofilm Formation
por: Kalivoda, Eric J., et al.
Publicado: (2013)

Review on the Pharmacological Properties of Phillyrin
por: Zhou, Chenyu, et al.
Publicado: (2022)

Identification and characterization of phosphodiesterases that specifically degrade 3′3′-cyclic GMP-AMP
por: Gao, Juyi, et al.
Publicado: (2015)

Dunce mutants of Drosophila melanogaster: mutants defective in the cyclic AMP phosphodiesterase enzyme system
Publicado: (1981)

The cyclic AMP phosphodiesterase RegA critically regulates encystation in social and pathogenic amoebas()
por: Du, Qingyou, et al.
Publicado: (2014)

Small-molecule allosteric activators of PDE4 long form cyclic AMP phosphodiesterases
por: Omar, Faisa, et al.
Publicado: (2019)

Cyclic AMP‐hydrolyzing phosphodiesterase inhibitors potentiate statin‐induced cancer cell death
por: Longo, Joseph, et al.
Publicado: (2020)

Bioactivity-Guided Extract Optimization of Osmanthus fragrans var. aurantiacus Leaves and Anti-Inflammatory Activities of Phillyrin
por: Song, Hwa-Young, et al.
Publicado: (2021)

Cyclic AMP Control Measured in Two Compartments in HEK293 Cells: Phosphodiesterase K(M) Is More Important than Phosphodiesterase Localization
por: Matthiesen, Karina, et al.
Publicado: (2011)

Unique Roles for Streptococcus pneumoniae Phosphodiesterase 2 in Cyclic di-AMP Catabolism and Macrophage Responses
por: Wooten, Alicia K., et al.
Publicado: (2020)

AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B
por: Johanns, M., et al.
Publicado: (2016)

Metabolome analysis of genus Forsythia related constituents in Forsythia suspensa leaves and fruits using UPLC-ESI-QQQ-MS/MS technique
por: Liu, Lingdi, et al.
Publicado: (2022)

Phillyrin Prevents Ovariectomy-Induced Osteolysis by Inhibiting Osteoclast Differentiation
por: Zhang, Geng, et al.
Publicado: (2022)

Spectra analysis and live-neuron imaging of cyclic AMP binding domain fusing circularly permutated GFP: Data for violet light excitable cyclic AMP indicator
por: Kawata, Seiko, et al.
Publicado: (2022)

Phosphodiesterases and cAMP Pathway in Pituitary Diseases
por: Bizzi, Mariana Ferreira, et al.
Publicado: (2019)

Phosphodiesterase type 4 anchoring regulates cAMP signaling to Popeye domain-containing proteins
por: Tibbo, Amy J., et al.
Publicado: (2022)

Two Phosphodiesterase Genes, PDEL and PDEH, Regulate Development and Pathogenicity by Modulating Intracellular Cyclic AMP Levels in Magnaporthe oryzae
por: Zhang, Haifeng, et al.
Publicado: (2011)

Functional Gene Module–Based Identification of Phillyrin as an Anticardiac Fibrosis Agent
por: Wang, Lei, et al.
Publicado: (2020)

Cyclic-di-AMP Phosphodiesterase Elicits Protective Immune Responses Against Mycobacterium tuberculosis H37Ra Infection in Mice
por: Lu, Yanzhi, et al.
Publicado: (2022)

Cyclic nucleotide specific phosphodiesterases of Leishmania major
por: Johner, Andrea, et al.
Publicado: (2006)

Cyclic nucleotide phosphodiesterases – 40 years of progress
por: Beavo, Joseph A, et al.
Publicado: (2009)

Role of Phosphodiesterase 5 and Cyclic GMP in Hypertension
por: Mergia, Evanthia, et al.
Publicado: (2016)

Cyclic nucleotide phosphodiesterase 1 and vascular aging
por: Yan, Chen
Publicado: (2015)

Phillyrin Attenuates Osteoclast Formation and Function and Prevents LPS-Induced Osteolysis in Mice
por: Wang, Jing, et al.
Publicado: (2019)

Antiviral effect and mechanism of Phillyrin and its reformulated FS21 against influenza
por: Chen, Yan, et al.
Publicado: (2023)

A Review of Red Yeast Rice, a Traditional Fermented Food in Japan and East Asia: Its Characteristic Ingredients and Application in the Maintenance and Improvement of Health in Lipid Metabolism and the Circulatory System
por: Fukami, Hiroyuki, et al.
Publicado: (2021)

Cyclic AMP Effectors in African Trypanosomes Revealed by Genome-Scale RNA Interference Library Screening for Resistance to the Phosphodiesterase Inhibitor CpdA
por: Gould, Matthew K., et al.
Publicado: (2013)

Phillyrin is an effective inhibitor of quorum sensing with potential as an anti-Pseudomonas aeruginosa infection therapy
por: ZHOU, Shuxin, et al.
Publicado: (2019)

Control of the cyclic GMP phosphodiesterase of frog photoreceptor membranes
Publicado: (1980)

Role of Cyclic Nucleotide Phosphodiesterases in Inner Ear and Hearing
por: Mittal, Rahul, et al.
Publicado: (2017)

Cyclic-AMP and bacterial cyclic-AMP receptor proteins revisited: adaptation for different ecological niches()
por: Green, Jeffrey, et al.
Publicado: (2014)

Utilization of different MurNAc sources by the oral pathogen Tannerella forsythia and role of the inner membrane transporter AmpG
por: Mayer, Valentina M. T., et al.
Publicado: (2020)

UPLC/Q-TOF MS Screening and Identification of Antibacterial Compounds in Forsythia suspensa (Thunb.) Vahl Leaves
por: Zhou, Mingyue, et al.
Publicado: (2022)

Landscape Population Genomics of Forsythia (Forsythia suspensa) Reveal That Ecological Habitats Determine the Adaptive Evolution of Species
por: Yang, Jie, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ef9r82gtsim2r0apd36e5mhccs