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Biochemical and Biophysical Characterization of Recombinant Human 3-Phosphoglycerate Dehydrogenase
The human enzyme D-3-phosphoglycerate dehydrogenase (hPHGDH) catalyzes the reversible dehydrogenation of 3-phosphoglycerate (3PG) into 3-phosphohydroxypyruvate (PHP) using the NAD(+)/NADH redox cofactor, the first step in the phosphorylated pathway producing L-serine. We focused on the full-length e...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073719/ https://www.ncbi.nlm.nih.gov/pubmed/33921788 http://dx.doi.org/10.3390/ijms22084231 |