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Biochemical and Biophysical Characterization of Recombinant Human 3-Phosphoglycerate Dehydrogenase

The human enzyme D-3-phosphoglycerate dehydrogenase (hPHGDH) catalyzes the reversible dehydrogenation of 3-phosphoglycerate (3PG) into 3-phosphohydroxypyruvate (PHP) using the NAD(+)/NADH redox cofactor, the first step in the phosphorylated pathway producing L-serine. We focused on the full-length e...

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Detalles Bibliográficos
Autores principales:	Murtas, Giulia, Marcone, Giorgia Letizia, Peracchi, Alessio, Zangelmi, Erika, Pollegioni, Loredano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073719/ https://www.ncbi.nlm.nih.gov/pubmed/33921788 http://dx.doi.org/10.3390/ijms22084231

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