ELISA- and Activity Assay-Based Quantification of BMP-2 Released In Vitro Can Be Biased by Solubility in “Physiological” Buffers and an Interfering Effect of Chitosan

Chitosan nanogel-coated polycaprolactone (PCL) fiber mat-based implant prototypes with tailored release of bone morphogenic protein 2 (BMP-2) are a promising approach to achieve implant-mediated bone regeneration. In order to ensure reliable in vitro release results, the robustness of a commercially...

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Detalles Bibliográficos
Autores principales: Sundermann, Julius, Sydow, Steffen, Burmeister, Laura, Hoffmann, Andrea, Menzel, Henning, Bunjes, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073737/
https://www.ncbi.nlm.nih.gov/pubmed/33921903
http://dx.doi.org/10.3390/pharmaceutics13040582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073737/
https://www.ncbi.nlm.nih.gov/pubmed/33921903
http://dx.doi.org/10.3390/pharmaceutics13040582

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