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House Dust Avoidance during Pregnancy and Subsequent Infant Development: The Japan Environment and Children’s Study

House dust, well known for causing allergy, contains chemicals that are harmful to fetal neurodevelopment. However, whether countermeasures for house dust allergy, such as frequent use of vacuum cleaners, frequent airing of futons, and the usage of anti-mite covers during pregnancy, are related to s...

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Autores principales: Matsumura, Kenta, Hamazaki, Kei, Tsuchida, Akiko, Inadera, Hidekuni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073752/
https://www.ncbi.nlm.nih.gov/pubmed/33920677
http://dx.doi.org/10.3390/ijerph18084277
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author Matsumura, Kenta
Hamazaki, Kei
Tsuchida, Akiko
Inadera, Hidekuni
author_facet Matsumura, Kenta
Hamazaki, Kei
Tsuchida, Akiko
Inadera, Hidekuni
author_sort Matsumura, Kenta
collection PubMed
description House dust, well known for causing allergy, contains chemicals that are harmful to fetal neurodevelopment. However, whether countermeasures for house dust allergy, such as frequent use of vacuum cleaners, frequent airing of futons, and the usage of anti-mite covers during pregnancy, are related to subsequent reduced risk of infant developmental delay remains unknown. Therefore, we examined this association by analyzing 81,106 mother-infant pairs who participated in a nationwide birth cohort in Japan. Infant developmental delays at 6 and 12 months postpartum were assessed using the Ages and Stages Questionnaire, Third Edition. A generalized linear model analysis was used to derive adjusted odds ratios (AORs) with the lowest care frequency as reference, while controlling 22 covariates. Our analysis showed that the above-mentioned cleaning measures were overall associated with a reduced risk of developmental delays, both at 6 and 12 months postpartum (AOR varied from 0.73 to 0.95, median: 0.84). Additionally, risks tended to decrease with an increase in the cleaning frequency. In conclusion, a negative dose-response association existed between these measures during pregnancy and infant developmental delay. Our results identify a potential role of frequent vacuum cleaning, airing bedding, and usage of anti-mite bedding covers in promoting intact infant development.
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spelling pubmed-80737522021-04-27 House Dust Avoidance during Pregnancy and Subsequent Infant Development: The Japan Environment and Children’s Study Matsumura, Kenta Hamazaki, Kei Tsuchida, Akiko Inadera, Hidekuni Int J Environ Res Public Health Article House dust, well known for causing allergy, contains chemicals that are harmful to fetal neurodevelopment. However, whether countermeasures for house dust allergy, such as frequent use of vacuum cleaners, frequent airing of futons, and the usage of anti-mite covers during pregnancy, are related to subsequent reduced risk of infant developmental delay remains unknown. Therefore, we examined this association by analyzing 81,106 mother-infant pairs who participated in a nationwide birth cohort in Japan. Infant developmental delays at 6 and 12 months postpartum were assessed using the Ages and Stages Questionnaire, Third Edition. A generalized linear model analysis was used to derive adjusted odds ratios (AORs) with the lowest care frequency as reference, while controlling 22 covariates. Our analysis showed that the above-mentioned cleaning measures were overall associated with a reduced risk of developmental delays, both at 6 and 12 months postpartum (AOR varied from 0.73 to 0.95, median: 0.84). Additionally, risks tended to decrease with an increase in the cleaning frequency. In conclusion, a negative dose-response association existed between these measures during pregnancy and infant developmental delay. Our results identify a potential role of frequent vacuum cleaning, airing bedding, and usage of anti-mite bedding covers in promoting intact infant development. MDPI 2021-04-17 /pmc/articles/PMC8073752/ /pubmed/33920677 http://dx.doi.org/10.3390/ijerph18084277 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Matsumura, Kenta
Hamazaki, Kei
Tsuchida, Akiko
Inadera, Hidekuni
House Dust Avoidance during Pregnancy and Subsequent Infant Development: The Japan Environment and Children’s Study
title House Dust Avoidance during Pregnancy and Subsequent Infant Development: The Japan Environment and Children’s Study
title_full House Dust Avoidance during Pregnancy and Subsequent Infant Development: The Japan Environment and Children’s Study
title_fullStr House Dust Avoidance during Pregnancy and Subsequent Infant Development: The Japan Environment and Children’s Study
title_full_unstemmed House Dust Avoidance during Pregnancy and Subsequent Infant Development: The Japan Environment and Children’s Study
title_short House Dust Avoidance during Pregnancy and Subsequent Infant Development: The Japan Environment and Children’s Study
title_sort house dust avoidance during pregnancy and subsequent infant development: the japan environment and children’s study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073752/
https://www.ncbi.nlm.nih.gov/pubmed/33920677
http://dx.doi.org/10.3390/ijerph18084277
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