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Spray-Dried Formulation of Epicertin, a Recombinant Cholera Toxin B Subunit Variant That Induces Mucosal Healing
Epicertin (EPT) is a recombinant variant of the cholera toxin B subunit, modified with a C-terminal KDEL endoplasmic reticulum retention motif. EPT has therapeutic potential for ulcerative colitis treatment. Previously, orally administered EPT demonstrated colon epithelial repair activity in dextran...
Autores principales: | Reeves, Micaela A., Royal, Joshua M., Morris, David A., Jurkiewicz, Jessica M., Matoba, Nobuyuki, Hamorsky, Krystal T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073836/ https://www.ncbi.nlm.nih.gov/pubmed/33919585 http://dx.doi.org/10.3390/pharmaceutics13040576 |
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