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Up-regulation of miR-155 potentiates CD34+ CML stem/progenitor cells to escape from the growth-inhibitory effects of TGF-ß1 and BMP signaling

microRNAs (miRNAs or miRs) play key roles in different stages of chronic myeloid leukemia (CML) pathogenesis. The present study aimed to demonstrate whether miR-155 enables CD34(+) CML cells to escape from the growth-inhibitory effects of TGF-β1 and bone morphogenetic protein (BMP) signaling. Among...

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Detalles Bibliográficos
Autores principales:	Mahdloo, Touba, Sahami, Pantea, Ramezani, Reihaneh, Jafarinia, Mojtaba, Goudarzi, Hamedreza, Babashah, Sadegh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Leibniz Research Centre for Working Environment and Human Factors 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073837/ https://www.ncbi.nlm.nih.gov/pubmed/33907541 http://dx.doi.org/10.17179/excli2021-3404

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