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Quality of Life in CKD Patients on Low-Protein Diets in a Multiple-Choice Diet System. Comparison between a French and an Italian Experience

Prescribing a low-protein diet (LPD) is part of the standard management of patients in advanced stages of chronic kidney disease (CKD). However, studies on the quality of life (QoL) of patients on LPDs are lacking, and the impact these diets have on their QoL is often given as a reason for not presc...

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Autores principales: Fois, Antioco, Torreggiani, Massimo, Trabace, Tiziana, Chatrenet, Antoine, Longhitano, Elisa, Mazé, Béatrice, Lippi, Francoise, Vigreux, Jerome, Beaumont, Coralie, Moio, Maria Rita, Piccoli, Giorgina Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073895/
https://www.ncbi.nlm.nih.gov/pubmed/33919635
http://dx.doi.org/10.3390/nu13041354
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author Fois, Antioco
Torreggiani, Massimo
Trabace, Tiziana
Chatrenet, Antoine
Longhitano, Elisa
Mazé, Béatrice
Lippi, Francoise
Vigreux, Jerome
Beaumont, Coralie
Moio, Maria Rita
Piccoli, Giorgina Barbara
author_facet Fois, Antioco
Torreggiani, Massimo
Trabace, Tiziana
Chatrenet, Antoine
Longhitano, Elisa
Mazé, Béatrice
Lippi, Francoise
Vigreux, Jerome
Beaumont, Coralie
Moio, Maria Rita
Piccoli, Giorgina Barbara
author_sort Fois, Antioco
collection PubMed
description Prescribing a low-protein diet (LPD) is part of the standard management of patients in advanced stages of chronic kidney disease (CKD). However, studies on the quality of life (QoL) of patients on LPDs are lacking, and the impact these diets have on their QoL is often given as a reason for not prescribing one. We, therefore, decided to assess the QoL in a cohort of CKD stage 3–5 patients followed up by a multiple-choice diet approach in an outpatient nephrology clinic in France. To do so, we used the short version of the World Health Organization’s quality of life questionnaire and compared the results with a historical cohort of Italian patients. We enrolled 153 patients, managed with tailored protein restriction in Le Mans, and compared them with 128 patients on similar diets who had been followed in Turin (Italy). We found there were no significant differences in terms of age (median 73 vs. 74 years, respectively), gender, CKD stage, and comorbidities (Charlson’s Comorbidity Index 7 vs. 6). French patients displayed a greater body mass index (29.0 vs. 25.4, p < 0.001) and prevalence of obesity (41.2 vs. 15.0%, p < 0.001). Baseline protein intake was over the target in France (1.2 g/kg of real body weight/day). In both cohorts, the burden of comorbidities was associated with poorer physical health perception while kidney function was inversely correlated to satisfaction with social life, independently of the type of diet. Our study suggests that the type of LPD they follow does not influence QoL in CKD patients and that a personalized approach towards protein restriction is feasible, even in elderly patients.
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spelling pubmed-80738952021-04-27 Quality of Life in CKD Patients on Low-Protein Diets in a Multiple-Choice Diet System. Comparison between a French and an Italian Experience Fois, Antioco Torreggiani, Massimo Trabace, Tiziana Chatrenet, Antoine Longhitano, Elisa Mazé, Béatrice Lippi, Francoise Vigreux, Jerome Beaumont, Coralie Moio, Maria Rita Piccoli, Giorgina Barbara Nutrients Article Prescribing a low-protein diet (LPD) is part of the standard management of patients in advanced stages of chronic kidney disease (CKD). However, studies on the quality of life (QoL) of patients on LPDs are lacking, and the impact these diets have on their QoL is often given as a reason for not prescribing one. We, therefore, decided to assess the QoL in a cohort of CKD stage 3–5 patients followed up by a multiple-choice diet approach in an outpatient nephrology clinic in France. To do so, we used the short version of the World Health Organization’s quality of life questionnaire and compared the results with a historical cohort of Italian patients. We enrolled 153 patients, managed with tailored protein restriction in Le Mans, and compared them with 128 patients on similar diets who had been followed in Turin (Italy). We found there were no significant differences in terms of age (median 73 vs. 74 years, respectively), gender, CKD stage, and comorbidities (Charlson’s Comorbidity Index 7 vs. 6). French patients displayed a greater body mass index (29.0 vs. 25.4, p < 0.001) and prevalence of obesity (41.2 vs. 15.0%, p < 0.001). Baseline protein intake was over the target in France (1.2 g/kg of real body weight/day). In both cohorts, the burden of comorbidities was associated with poorer physical health perception while kidney function was inversely correlated to satisfaction with social life, independently of the type of diet. Our study suggests that the type of LPD they follow does not influence QoL in CKD patients and that a personalized approach towards protein restriction is feasible, even in elderly patients. MDPI 2021-04-18 /pmc/articles/PMC8073895/ /pubmed/33919635 http://dx.doi.org/10.3390/nu13041354 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Fois, Antioco
Torreggiani, Massimo
Trabace, Tiziana
Chatrenet, Antoine
Longhitano, Elisa
Mazé, Béatrice
Lippi, Francoise
Vigreux, Jerome
Beaumont, Coralie
Moio, Maria Rita
Piccoli, Giorgina Barbara
Quality of Life in CKD Patients on Low-Protein Diets in a Multiple-Choice Diet System. Comparison between a French and an Italian Experience
title Quality of Life in CKD Patients on Low-Protein Diets in a Multiple-Choice Diet System. Comparison between a French and an Italian Experience
title_full Quality of Life in CKD Patients on Low-Protein Diets in a Multiple-Choice Diet System. Comparison between a French and an Italian Experience
title_fullStr Quality of Life in CKD Patients on Low-Protein Diets in a Multiple-Choice Diet System. Comparison between a French and an Italian Experience
title_full_unstemmed Quality of Life in CKD Patients on Low-Protein Diets in a Multiple-Choice Diet System. Comparison between a French and an Italian Experience
title_short Quality of Life in CKD Patients on Low-Protein Diets in a Multiple-Choice Diet System. Comparison between a French and an Italian Experience
title_sort quality of life in ckd patients on low-protein diets in a multiple-choice diet system. comparison between a french and an italian experience
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073895/
https://www.ncbi.nlm.nih.gov/pubmed/33919635
http://dx.doi.org/10.3390/nu13041354
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