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Polymorphism on human aromatase affects protein dynamics and substrate binding: spectroscopic evidence
Human aromatase is a member of the cytochrome P450 superfamily, involved in steroid hormones biosynthesis. In particular, it converts androgen into estrogens being therefore responsible for the correct sex steroids balance. Due to its capacity in producing estrogens it has also been considered as a...
Autores principales: | Di Nardo, Giovanna, Di Venere, Almerinda, Zhang, Chao, Nicolai, Eleonora, Castrignanò, Silvia, Di Paola, Luisa, Gilardi, Gianfranco, Mei, Giampiero |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073906/ https://www.ncbi.nlm.nih.gov/pubmed/33902660 http://dx.doi.org/10.1186/s13062-021-00292-9 |
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