Diffuse Idiopathic Skeletal Hyperostosis of Cervical Spine with Dysphagia—Molecular and Clinical Aspects

Diffuse idiopathic skeletal hyperostosis (DISH) is a condition characterized by the calcification and ossification of the ligaments of the cervical spine; in some cases, it may result in dysphagia. The condition is more common in men over 50 years of age with metabolic disorders, and it is often asy...

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Detalles Bibliográficos
Autores principales: Dąbrowski, Mikołaj, Kubaszewski, Łukasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074005/
https://www.ncbi.nlm.nih.gov/pubmed/33923907
http://dx.doi.org/10.3390/ijms22084255
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author Dąbrowski, Mikołaj
Kubaszewski, Łukasz
author_facet Dąbrowski, Mikołaj
Kubaszewski, Łukasz
author_sort Dąbrowski, Mikołaj
collection PubMed
description Diffuse idiopathic skeletal hyperostosis (DISH) is a condition characterized by the calcification and ossification of the ligaments of the cervical spine; in some cases, it may result in dysphagia. The condition is more common in men over 50 years of age with metabolic disorders, and it is often asymptomatic and not a major issue for patients. The etiology of DISH is poorly understood, and known genetic factors indicate multiple signal pathways and multigene inheritance. In this review, we discuss the epidemiological, clinical, and etiological aspects of DISH with a special focus on dysphagia.
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spelling pubmed-80740052021-04-27 Diffuse Idiopathic Skeletal Hyperostosis of Cervical Spine with Dysphagia—Molecular and Clinical Aspects Dąbrowski, Mikołaj Kubaszewski, Łukasz Int J Mol Sci Review Diffuse idiopathic skeletal hyperostosis (DISH) is a condition characterized by the calcification and ossification of the ligaments of the cervical spine; in some cases, it may result in dysphagia. The condition is more common in men over 50 years of age with metabolic disorders, and it is often asymptomatic and not a major issue for patients. The etiology of DISH is poorly understood, and known genetic factors indicate multiple signal pathways and multigene inheritance. In this review, we discuss the epidemiological, clinical, and etiological aspects of DISH with a special focus on dysphagia. MDPI 2021-04-20 /pmc/articles/PMC8074005/ /pubmed/33923907 http://dx.doi.org/10.3390/ijms22084255 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Dąbrowski, Mikołaj
Kubaszewski, Łukasz
Diffuse Idiopathic Skeletal Hyperostosis of Cervical Spine with Dysphagia—Molecular and Clinical Aspects
title Diffuse Idiopathic Skeletal Hyperostosis of Cervical Spine with Dysphagia—Molecular and Clinical Aspects
title_full Diffuse Idiopathic Skeletal Hyperostosis of Cervical Spine with Dysphagia—Molecular and Clinical Aspects
title_fullStr Diffuse Idiopathic Skeletal Hyperostosis of Cervical Spine with Dysphagia—Molecular and Clinical Aspects
title_full_unstemmed Diffuse Idiopathic Skeletal Hyperostosis of Cervical Spine with Dysphagia—Molecular and Clinical Aspects
title_short Diffuse Idiopathic Skeletal Hyperostosis of Cervical Spine with Dysphagia—Molecular and Clinical Aspects
title_sort diffuse idiopathic skeletal hyperostosis of cervical spine with dysphagia—molecular and clinical aspects
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074005/
https://www.ncbi.nlm.nih.gov/pubmed/33923907
http://dx.doi.org/10.3390/ijms22084255
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AT kubaszewskiłukasz diffuseidiopathicskeletalhyperostosisofcervicalspinewithdysphagiamolecularandclinicalaspects

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