Coordinated and Independent Roles for MLH Subunits in DNA Repair

The MutL family of DNA mismatch repair proteins (MMR) acts to maintain genomic integrity in somatic and meiotic cells. In baker’s yeast, the MutL homolog (MLH) MMR proteins form three heterodimeric complexes, MLH1-PMS1, MLH1-MLH2, and MLH1-MLH3. The recent discovery of human PMS2 (homolog of baker’s...

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Detalles Bibliográficos
Autores principales: Pannafino, Gianno, Alani, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074049/
https://www.ncbi.nlm.nih.gov/pubmed/33923939
http://dx.doi.org/10.3390/cells10040948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074049/
https://www.ncbi.nlm.nih.gov/pubmed/33923939
http://dx.doi.org/10.3390/cells10040948

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