Unique Regulation of Intestinal Villus Epithelial Cl(−)/HCO(3)(−) Exchange by Cyclooxygenase Pathway Metabolites of Arachidonic Acid in a Mouse Model of Spontaneous Ileitis

Electrolytes (NaCl) and fluid malabsorption cause diarrhea in inflammatory bowel disease (IBD). Coupled NaCl absorption, mediated by Na(+)/H(+) and Cl(−)/HCO(3)(−) exchanges on the intestinal villus cells brush border membrane (BBM), is inhibited in IBD. Arachidonic acid metabolites (AAMs) formed vi...

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Detalles Bibliográficos
Autores principales: Rahman, M Motiur, Borthakur, Alip, Afroz, Sheuli, Arthur, Subha, Sundaram, Uma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074161/
https://www.ncbi.nlm.nih.gov/pubmed/33920650
http://dx.doi.org/10.3390/ijms22084171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074161/
https://www.ncbi.nlm.nih.gov/pubmed/33920650
http://dx.doi.org/10.3390/ijms22084171

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