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Single-cell characterization of a model of poly I:C-stimulated peripheral blood mononuclear cells in severe asthma
BACKGROUND: Asthma has been associated with impaired interferon response. Multiple cell types have been implicated in such response impairment and may be responsible for asthma immunopathology. However, existing models to study the immune response in asthma are limited by bulk profiling of cells. Ou...
Autores principales: | Chen, Ailu, Diaz-Soto, Maria P., Sanmamed, Miguel F., Adams, Taylor, Schupp, Jonas C., Gupta, Amolika, Britto, Clemente, Sauler, Maor, Yan, Xiting, Liu, Qing, Nino, Gustavo, Cruz, Charles S. Dela, Chupp, Geoffrey L., Gomez, Jose L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074196/ https://www.ncbi.nlm.nih.gov/pubmed/33902571 http://dx.doi.org/10.1186/s12931-021-01709-9 |
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