Cargando…

The role of RNA m(6)A methylation in the regulation of postnatal hypoxia-induced pulmonary hypertension

BACKGROUND: Pulmonary hypertension (PH) is a complex pulmonary vascular disease characterized by an imbalance in vasoconstrictor/vasodilator signaling within the pulmonary vasculature. Recent evidence suggests that exposure to hypoxia early in life can cause alterations in the pulmonary vasculature...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Shanshan, Xu, Xuefeng, Zhang, Ziming, Yan, Lingling, Zhang, Liyan, Du, Lizhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074209/ https://www.ncbi.nlm.nih.gov/pubmed/33902609 http://dx.doi.org/10.1186/s12931-021-01728-6

Ejemplares similares

Epigenetic Regulation and Its Therapeutic Potential in Pulmonary Hypertension
por: Wang, Yu, et al.
Publicado: (2018)

PVECs‐Derived Exosomal microRNAs Regulate PASMCs via FoxM1 Signaling in IUGR‐induced Pulmonary Hypertension
por: Luo, Xiaofei, et al.
Publicado: (2022)

Increased Expression of MicroRNA‐206 Inhibits Potassium Voltage‐Gated Channel Subfamily A Member 5 in Pulmonary Arterial Smooth Muscle Cells and Is Related to Exaggerated Pulmonary Artery Hypertension Following Intrauterine Growth Retardation in Rats
por: Lv, Ying, et al.
Publicado: (2019)

Unique and Specific m(6)A RNA Methylation in Mouse Embryonic and Postnatal Cerebral Cortices
por: Zhang, Longbin, et al.
Publicado: (2020)

RNA m(6)A methylation participates in regulation of postnatal development of the mouse cerebellum
por: Ma, Chunhui, et al.
Publicado: (2018)

Genes in pediatric pulmonary arterial hypertension and the most promising BMPR2 gene therapy
por: Dai, Lingling, et al.
Publicado: (2022)

mRNA N(6)-methyladenosine methylation of postnatal liver development in pig
por: He, Shen, et al.
Publicado: (2017)

Integrated analysis of m(6)A mRNA methylation in rats with monocrotaline-induced pulmonary arterial hypertension
por: Zeng, Yunhong, et al.
Publicado: (2021)

LncRNA FENDRR with m6A RNA methylation regulates hypoxia-induced pulmonary artery endothelial cell pyroptosis by mediating DRP1 DNA methylation
por: Wang, Xiaoying, et al.
Publicado: (2022)

SEDT2/METTL14-mediated m6A methylation awakening contributes to hypoxia-induced pulmonary arterial hypertension in mice
por: Zhou, Xue-Liang, et al.
Publicado: (2021)

Identification of the Key Pathways and Genes in Hypoxia Pulmonary Arterial Hypertension Following Intrauterine Growth Retardation
por: Zhu, Weifen, et al.
Publicado: (2022)

RNA methylation-related genes of m6A, m5C, and m1A predict prognosis and immunotherapy response in cervical cancer
por: Wang, Yan, et al.
Publicado: (2023)

Mettl3-mediated mRNA m(6)A modification controls postnatal liver development by modulating the transcription factor Hnf4a
por: Xu, Yan, et al.
Publicado: (2022)

Comprehensive analyses of m6A RNA methylation patterns and related immune microenvironment in idiopathic pulmonary arterial hypertension
por: Gao, Gufeng, et al.
Publicado: (2023)

The role of regulators of RNA m(6)A methylation in lung cancer
por: Zhang, Qicheng, et al.
Publicado: (2022)

Prognostic Implication of the m(6)A RNA Methylation Regulators in Rectal Cancer
por: Chen, Yajie, et al.
Publicado: (2021)

Crosstalk Between Histone and m(6)A Modifications and Emerging Roles of m(6)A RNA Methylation
por: Xu, Zibin, et al.
Publicado: (2022)

Transcriptome-wide map of m(6)A circRNAs identified in a rat model of hypoxia mediated pulmonary hypertension
por: Su, Hua, et al.
Publicado: (2020)

Postnatal causes and severity of persistent pulmonary Hypertension of Newborn
por: Arshad, Muhammad Sohail, et al.
Publicado: (2021)

A prediction model of pulmonary hypertension in preterm infants with bronchopulmonary dysplasia
por: Wang, Chenhong, et al.
Publicado: (2022)

The role of mRNA m(6)A methylation in the nervous system
por: Li, Jiashuo, et al.
Publicado: (2019)

Emerging Roles for DNA 6mA and RNA m6A Methylation in Mammalian Genome
por: Xie, Leijie, et al.
Publicado: (2023)

The Mechanism of Volatile Oil of Rhodiola tangutica against Hypoxia-Induced Pulmonary Hypertension in Rats Based on RAS Pathway
por: Nan, Xingmei, et al.
Publicado: (2022)

Crosstalk among m(6)A RNA methylation, hypoxia and metabolic reprogramming in TME: from immunosuppressive microenvironment to clinical application
por: Zhang, Fusheng, et al.
Publicado: (2022)

RNA m(6)A methylation in cancer
por: Wang, Zhaotong, et al.
Publicado: (2022)

Downregulation of microRNA-637 Increases Risk of Hypoxia-Induced Pulmonary Hypertension by Modulating Expression of Cyclin Dependent Kinase 6 (CDK6) in Pulmonary Smooth Muscle Cells
por: Sang, Hai-yan, et al.
Publicado: (2016)

Essential Genes and MiRNA–mRNA Network Contributing to the Pathogenesis of Idiopathic Pulmonary Arterial Hypertension
por: Hao, Shengyu, et al.
Publicado: (2021)

Impact of interleukin-6 on hypoxia-induced pulmonary hypertension and lung inflammation in mice
por: Savale, Laurent, et al.
Publicado: (2009)

Interleukin-6 trans-signaling contributes to chronic hypoxia-induced pulmonary hypertension
por: Maston, Levi D., et al.
Publicado: (2018)

Comprehensive Analyses of miRNA-mRNA Network and Potential Drugs in Idiopathic Pulmonary Arterial Hypertension
por: Li, Chan, et al.
Publicado: (2020)

MSCs Therapy Reverse the Gut Microbiota in Hypoxia-Induced Pulmonary Hypertension Mice
por: Luo, Lingjie, et al.
Publicado: (2021)

Comprehensive analysis of the expression of N6-methyladenosine RNA methylation regulators in pulmonary artery hypertension
por: Zheng, Hao, et al.
Publicado: (2022)

Nocturnal hypoxia in patients with idiopathic pulmonary arterial hypertension
por: Yan, Lu, et al.
Publicado: (2020)

A Critical Role of the mTOR/eIF2α Pathway in Hypoxia-Induced Pulmonary Hypertension
por: Wang, Ai-ping, et al.
Publicado: (2015)

Decoding ceRNA regulatory network in the pulmonary artery of hypoxia-induced pulmonary hypertension (HPH) rat model
por: Wang, Jun, et al.
Publicado: (2022)

m6A RNA methylation regulators could contribute to the occurrence of chronic obstructive pulmonary disease
por: Huang, Xinwei, et al.
Publicado: (2020)

Pulmonary Artery Smooth Muscle Cell Senescence Promotes the Proliferation of PASMCs by Paracrine IL-6 in Hypoxia-Induced Pulmonary Hypertension
por: Wang, Ai-Ping, et al.
Publicado: (2021)

Tsantan Sumtang Alleviates Chronic Hypoxia-Induced Pulmonary Hypertension by Inhibiting Proliferation of Pulmonary Vascular Cells
por: He, Qilian, et al.
Publicado: (2018)

Abnormality of m6A mRNA Methylation Is Involved in Alzheimer’s Disease
por: Han, Min, et al.
Publicado: (2020)

m6A RNA Methylation Regulators Contribute to Predict and as a Therapy Target of Pulmonary Fibrosis
por: Deng, Meng-Sheng, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_9u5dniaslftu88qg2a9e42qoga