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Targeting lactate dehydrogenase a improves radiotherapy efficacy in non-small cell lung cancer: from bedside to bench
BACKGROUND: Lactate dehydrogenase A (LDHA) is overexpressed and associated with poor prognosis in many kinds of cancer. In the current study, we evaluated the prognostic value of LDHA expression in non-small cell lung cancer (NSCLC), and tested whether LDHA inhibition might improve radiotherapy effi...
Autores principales: | Yang, Yang, Chong, Yu, Chen, Mengyuan, Dai, Wumin, Zhou, Xia, Ji, Yongling, Qiu, Guoqin, Du, Xianghui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074241/ https://www.ncbi.nlm.nih.gov/pubmed/33902615 http://dx.doi.org/10.1186/s12967-021-02825-2 |
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