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Revisiting the Impact of Local Leptin Signaling in Folliculogenesis and Oocyte Maturation in Obese Mothers

The complex nature of folliculogenesis regulation accounts for its susceptibility to maternal physiological fitness. In obese mothers, progressive expansion of adipose tissue culminates with severe hyperestrogenism and hyperleptinemia with detrimental effects for ovarian performance. Indeed, materna...

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Detalles Bibliográficos
Autores principales: Wołodko, Karolina, Castillo-Fernandez, Juan, Kelsey, Gavin, Galvão, António
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074257/
https://www.ncbi.nlm.nih.gov/pubmed/33924072
http://dx.doi.org/10.3390/ijms22084270