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The Characterization of a Subependymal Giant Astrocytoma-Like Cell Line from Murine Astrocyte with mTORC1 Hyperactivation

Tuberous sclerosis complex (TSC) is a genetic disorder caused by inactivating mutations in TSC1 (hamartin) or TSC2 (tuberin), crucial negative regulators of the mechanistic target of rapamycin complex 1 (mTORC1) signaling pathway. TSC affects multiple organs including the brain. The neurologic manif...

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Detalles Bibliográficos
Autores principales:	Tang, Xin, Angst, Gabrielle, Haas, Michael, Yang, Fuchun, Wang, Chenran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074262/ https://www.ncbi.nlm.nih.gov/pubmed/33923449 http://dx.doi.org/10.3390/ijms22084116

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