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Modified Oligonucleotides: New Structures, New Properties, and New Spheres of Application
Nucleic acids have made a long and arduous journey “from the bench to the bedside.” At present, it can be assumed that drugs based on modified oligonucleotides will find a worthy application in personalized medicine of the future.
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pleiades Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074280/ https://www.ncbi.nlm.nih.gov/pubmed/33935479 http://dx.doi.org/10.1134/S1068162021020175 |
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author | Metelev, V. G. Oretskaya, T. S. |
author_facet | Metelev, V. G. Oretskaya, T. S. |
author_sort | Metelev, V. G. |
collection | PubMed |
description | Nucleic acids have made a long and arduous journey “from the bench to the bedside.” At present, it can be assumed that drugs based on modified oligonucleotides will find a worthy application in personalized medicine of the future. |
format | Online Article Text |
id | pubmed-8074280 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Pleiades Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-80742802021-04-26 Modified Oligonucleotides: New Structures, New Properties, and New Spheres of Application Metelev, V. G. Oretskaya, T. S. Russ J Bioorg Chem Article Nucleic acids have made a long and arduous journey “from the bench to the bedside.” At present, it can be assumed that drugs based on modified oligonucleotides will find a worthy application in personalized medicine of the future. Pleiades Publishing 2021-04-26 2021 /pmc/articles/PMC8074280/ /pubmed/33935479 http://dx.doi.org/10.1134/S1068162021020175 Text en © Pleiades Publishing, Ltd. 2021, ISSN 1068-1620, Russian Journal of Bioorganic Chemistry, 2021, Vol. 47, No. 2, pp. 339–343. © Pleiades Publishing, Ltd., 2021.Russian Text © The Author(s), 2021, published in Bioorganicheskaya Khimiya, 2021, Vol. 47, No. 2, pp. 179–183. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Article Metelev, V. G. Oretskaya, T. S. Modified Oligonucleotides: New Structures, New Properties, and New Spheres of Application |
title | Modified Oligonucleotides: New Structures, New Properties, and New Spheres of Application |
title_full | Modified Oligonucleotides: New Structures, New Properties, and New Spheres of Application |
title_fullStr | Modified Oligonucleotides: New Structures, New Properties, and New Spheres of Application |
title_full_unstemmed | Modified Oligonucleotides: New Structures, New Properties, and New Spheres of Application |
title_short | Modified Oligonucleotides: New Structures, New Properties, and New Spheres of Application |
title_sort | modified oligonucleotides: new structures, new properties, and new spheres of application |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074280/ https://www.ncbi.nlm.nih.gov/pubmed/33935479 http://dx.doi.org/10.1134/S1068162021020175 |
work_keys_str_mv | AT metelevvg modifiedoligonucleotidesnewstructuresnewpropertiesandnewspheresofapplication AT oretskayats modifiedoligonucleotidesnewstructuresnewpropertiesandnewspheresofapplication |