Association of plasma mitochondrial DNA with COPD severity and progression in the SPIROMICS cohort

BACKGROUND: There is a lack of mechanism-driven, clinically relevant biomarkers in chronic obstructive pulmonary disease (COPD). Mitochondrial dysfunction, a proposed disease mechanism in COPD, is associated with the release of mitochondrial DNA (mtDNA), but plasma cell-free mtDNA has not been previ...

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Detalles Bibliográficos
Autores principales: Zhang, William Z., Hoffman, Katherine L., Schiffer, Kristen T., Oromendia, Clara, Rice, Michelle C., Barjaktarevic, Igor, Peters, Stephen P., Putcha, Nirupama, Bowler, Russell P., Wells, J. Michael, Couper, David J., Labaki, Wassim W., Curtis, Jeffrey L., Han, Meilan K., Paine, Robert, Woodruff, Prescott G., Criner, Gerard J., Hansel, Nadia N., Diaz, Ivan, Ballman, Karla V., Nakahira, Kiichi, Choi, Mary E., Martinez, Fernando J., Choi, Augustine M. K., Cloonan, Suzanne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074408/
https://www.ncbi.nlm.nih.gov/pubmed/33902556
http://dx.doi.org/10.1186/s12931-021-01707-x

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