Accelerated global sensitivity analysis of genome-wide constraint-based metabolic models

BACKGROUND: Genome-wide reconstructions of metabolism opened the way to thorough investigations of cell metabolism for health care and industrial purposes. However, the predictions offered by Flux Balance Analysis (FBA) can be strongly affected by the choice of flux boundaries, with particular regar...

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Detalles Bibliográficos
Autores principales: Nobile, Marco S., Coelho, Vasco, Pescini, Dario, Damiani, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074438/
https://www.ncbi.nlm.nih.gov/pubmed/33902438
http://dx.doi.org/10.1186/s12859-021-04002-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074438/
https://www.ncbi.nlm.nih.gov/pubmed/33902438
http://dx.doi.org/10.1186/s12859-021-04002-0

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