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Accelerated global sensitivity analysis of genome-wide constraint-based metabolic models
BACKGROUND: Genome-wide reconstructions of metabolism opened the way to thorough investigations of cell metabolism for health care and industrial purposes. However, the predictions offered by Flux Balance Analysis (FBA) can be strongly affected by the choice of flux boundaries, with particular regar...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074438/ https://www.ncbi.nlm.nih.gov/pubmed/33902438 http://dx.doi.org/10.1186/s12859-021-04002-0 |